Ptpn5 Antibodies

AND Ptpn5 ELISA kits, Ptpn5 Proteins

Many biological assays use antibodies to detect Ptpn5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ptpn5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ptpn5 antibodies...

We validate the specificity of these antibodies to Ptpn5 by testing them on tissues known to express Ptpn5 positively and negatively. Browse below to find the Ptpn5 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Ptpn5 Infographic by Boster Bio

All Ptpn5 Products

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Anti-PTPN5 Antibody

Western blot analysis of PTPN5 in Jurkat cell lysate with PTPN5 antibody at (A) 1 and (B) 2 μg/ml

Immunohistochemistry of PTPN5 in mouse brain tissue with PTPN5 antibody at 5 μg/ml

Immunofluorescence of PTPN5 in mouse brain tissue with PTPN5 antibody at 20 μg/ml

Human, Mouse

ELISA, IF, IHC-P, WB

$481
Cat # A05405
0.1 mg

PTPN5 (NM_006906) Human Over-expression Lysate

PTPN5 Human Over-expression Lysates NM_001039970

Human

$628
Cat # LS084867
20 µg, 100 µg

Ptpn5 Overview

Facts about Tyrosine-protein phosphatase non-receptor type 5.

Tyrosine-protein phosphatase non-receptor type 5 (Ptpn5)

May regulate the action of several effector molecules involved in synaptic plasticity and neuronal cell survival, such as MAPKs, Src family kinases and NMDA receptors. .

Gene Information

Mouse
Gene Name:	Ptpn5
Uniprot:	P54830
Entrez:	19259

Family

Belongs to:

protein-tyrosine phosphatase family

Alternative Names

EC 3.1.3.48; FLJ14427; Neural-specific protein-tyrosine phosphatase; protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched); protein-tyrosine phosphatase striatum-enriched; STEPPTPSTEP; Striatum-enriched protein-tyrosine phosphatase; tyrosine-protein phosphatase non-receptor type 5

Molecular Weight

Mass (kDA):
60.815 kDA

Genomic Context


Mouse

Location:	7 B3\|7 30.7 cM
Sequence:	7;

Tissue Specificity

STEP20 is expressed only in the CNS.

Diseases

Nervousness
Alzheimer's Disease
Posttransfusion Purpura
Depressive Disorder
Epilepsy
Fragile X Syndrome
Ischemia
Amnesia
Huntington Disease
Pain
Neurofibrillary Tangles
Stress, Psychological
Mental Disorders

Brain Diseases
Neuropathology Disease
Neurodegenerative Disorders
Cerebrovascular Accident
Status Epilepticus
Plaque, Amyloid
Stereotyped Behavior

Pathways

Endocytosis
Localization
Proteolysis
Synaptic Transmission
Translation
Receptor Internalization
Cell Death
Cell Adhesion
Protein Phosphorylation
Regulation Of Cell Adhesion
Regeneration

Neuroprotection
Sensitization
Cellular Localization
Cognition
Exocytosis
Rna Interference

PTMs

Phosphorylation
Dephosphorylation

Cleavage
Ubiquitination

Biotinylation

Research Areas

Alzheimers Research
Cancer
Cellular Markers
Hypoxia
Neurodegeneration

Neuroscience
Protein Phosphatase
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Ptpn5

References

PMID: 7494467 by Sharma E., et al. Identification of two alternatively spliced transcripts of STEP: a subfamily of brain-enriched protein tyrosine phosphatases.

PMID: 8987810 by Bult A., et al. STEP61: a member of a family of brain-enriched PTPs is localized to the endoplasmic reticulum.