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- Table of Contents
GTP-binding protein Rit1 Antibodies
AND RIT1 ELISA kits, GTP-binding protein Rit1 Proteins
Many biological assays use antibodies to detect GTP-binding protein Rit1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GTP-binding protein Rit1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GTP-binding protein Rit1 antibodies...
Designing an IHC experiment for GTP-binding protein Rit1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the RIT1 IHC GuideRIT1 Infographic by Boster Bio
All RIT1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
ELISA
$480
Cat # EKC1507
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1507
1 kit, containing one 96-well plate and all necessary reagents
RIT1 Overview
Facts about GTP-binding protein Rit1.
GTP-binding protein Rit1 (RIT1)
Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF- dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a huge selection of cellular functions, including cell proliferation, survival, and differentiation.
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Gene Information
| Human | |
|---|---|
| Gene Name: | RIT1 |
| Uniprot: | Q92963 |
| Entrez: | 6016 |
Family
| Belongs to: |
|---|
| small GTPase superfamily |
Alternative Names
GTP-binding protein Rit1; GTP-binding protein Roc1; MGC125864; MGC125865; Ras-like protein expressed in many tissues; Ras-like without CAAX 1; Ras-like without CAAX protein 1; RIBB; RIBBRIT; Ric-like, expressed in many tissues; RIT; Rit1; ROC1; ROC1Ric (Drosophila)-like, expressed in many tissues
Molecular Weight
Mass (kDA):
25.145 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q22 |
| Sequence: | 1; NC_000001.11 (155897808..155911349, complement) |
Tissue Specificity
Expressed in many tissues.
Subcellular Localizations
Cell membrane.
Diseases
- Neoplasms
- Malignant Neoplasms
- Cell Transformation, Neoplastic
- Neoplasms, Radiation-induced
- Thymus Neoplasms
- Lymphoma
- Leukemia
- Carcinoma
- Carcinogenesis
- Nervousness
- Leukemogenesis
- Liver Carcinoma
- Metaplastic Cell Transformation
Interacting Proteins
- RLF
Pathways
- Cell Growth
- Response To Oxidative Stress
- Translation
- Regeneration
- Transport
- Gene Silencing
- Regulation Of Signaling
- Immune Response
- Cell Fate Determination
- Neurogenesis
- Calcium-mediated Signaling
- Cell Cycle
- Nitrogen Fixation
PTMs
- Phosphorylation
- Farnesylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RIT1
bosterbio.com/bosterbio-gene-info-cards/RIT1
References
PMID: 8824319 by Lee C.H.J., et al. Rin, a neuron-specific and calmodulin-binding small G-protein, and Rit define a novel subfamily of ras proteins.
PMID: 8918462 by Wes P.D., et al. RIC, a calmodulin-binding Ras-like GTPase.