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- Table of Contents
Facts about Tyrosine-protein kinase transmembrane receptor ROR2.
Phosphorylates YWHAB, resulting in induction of osteogenesis and bone formation (PubMed:17717073). By comparison, has also been demonstrated to possess very little tyrosine kinase activity in vitro.
| Human | |
|---|---|
| Gene Name: | ROR2 |
| Uniprot: | Q01974 |
| Entrez: | 4920 |

| Belongs to: |
|---|
| protein kinase superfamily |

BDB; BDB1; EC 2.7.10.1; MGC163394; neurotrophic tyrosine kinase receptor-related 2; Neurotrophic tyrosine kinase, receptor-related 2; NTRKR2; NTRKR2tyrosine-protein kinase transmembrane receptor ROR2; receptor tyrosine kinase-like orphan receptor 2; ROR2
Mass (kDA):
104.757 kDA

| Human | |
|---|---|
| Location: | 9q22.31 |
| Sequence: | 9; NC_000009.12 (91722598..91950228, complement) |
Cell membrane; Single-pass type I membrane protein.






PMID: 1334494 by Masiakowski P., et al. A novel family of cell surface receptors with tyrosine kinase-like domain.
PMID: 10700182 by Oldridge M., et al. Dominant mutations in ROR2, encoding an orphan receptor tyrosine kinase, cause brachydactyly type B.