Homeobox protein SIX5 (Six5)

Transcription factor that is considered to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation.

Binds a 5'-GGTGTCAG-3' motif present in the ARE regulatory element of ATP1A1. Binds a 5'- TCA[AG][AG]TTNC-3' motif present in the MEF3 element from the myogenin promoter, and at the IGFBP5 promoter (By similarity).