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- Table of Contents
Facts about Trinucleotide repeat-containing gene 6A protein.
As a scaffolding protein, associates with argonaute proteins bound to partially complementary mRNAs, and can simultaneously recruit CCR4-NOT and PAN deadenylase complexes. .
Human | |
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Gene Name: | TNRC6A |
Uniprot: | Q8NDV7 |
Entrez: | 27327 |
Belongs to: |
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GW182 family |
CAG repeat protein 26; CAGH26FLJ22043; DKFZp666E117; EMSY interactor protein; Glycine-tryptophan protein of 182 kDa; GW182 autoantigen; GW182GW1; KIAA1460EDIE; MGC75384; Protein GW1; TNRC6; trinucleotide repeat containing 6; trinucleotide repeat containing 6A; trinucleotide repeat-containing gene 6A protein
Mass (kDA):
210.297 kDA
Human | |
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Location: | 16p12.1 |
Sequence: | 16; NC_000016.10 (24610205..24826223) |
Ubiquitous.
Cytoplasm, P-body. Mammalian P-bodies are also known as GW bodies (GWBs).
PMID: 11950943 by Eystathioy T., et al. A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles.
PMID: 9225980 by Margolis R.L., et al. cDNAs with long CAG trinucleotide repeats from human brain.