Product Info Summary
SKU: | A02797-2 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Monkey, Mouse |
Host: | Rabbit |
Application: | ELISA, IHC, WB |
Customers Who Bought This Also Bought
Product info
Product Name
Anti-5'-3' exoribonuclease 2 XRN2 Antibody
SKU/Catalog Number
A02797-2
Size
100ul
Form
Liquid
Description
Boster Bio Anti-5'-3' exoribonuclease 2 XRN2 Antibody catalog # A02797-2. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Monkey, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-5'-3' exoribonuclease 2 XRN2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02797-2)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human XRN2
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02797-2 is reactive to XRN2 in Human, Monkey, Mouse
Applications
A02797-2 is guaranteed for ELISA, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
108.582kDa
Background of XRN2
The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARFof CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARFof CDKN2A By similarity. Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
Hiroyasu Inada, J. Cell Biol., Oct 2001; 155: 415.
Kenneth M. Izumi, Mol. Cell. Biol., Aug 1999; 19: 5759 - 5767.
Susumu Rokudai, Mol. Cell. Biol., Dec 2002; 22: 8695 - 8708.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
Submit A Review
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-5'-3' exoribonuclease 2 XRN2 Antibody A02797-2
Western Blot (WB) analysis of specific cells using XRN2 polyclonal antibody.Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For XRN2 (Source: Uniprot.org, NCBI)
Gene Name
XRN2
Full Name
5'-3' exoribonuclease 2
Weight
108.582kDa
Superfamily
5'-3' exonuclease family
Alternative Names
5'-3' exoribonuclease 2; Dhm1-like protein (mouse homolog); DHM1-like protein; DHP protein; EC 3.1.13; EC 3.1.13.- XRN2 5-3 exoribonuclease 2 5-3 exoribonuclease 2|DHM1-like protein|DHP protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on XRN2, check out the XRN2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for XRN2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-5'-3' exoribonuclease 2 XRN2 Antibody (A02797-2)
Hello CJ!
No publications found for A02797-2
*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.
Recommended Resources
Here are featured tools and databases that you might find useful.
- Boster's Pathways Library
- Protein Databases
- Bioscience Research Protocol Resources
- Data Processing & Analysis Software
- Photo Editing Software
- Scientific Literature Resources
- Research Paper Management Tools
- Molecular Biology Software
- Primer Design Tools
- Bioinformatics Tools
- Phylogenetic Tree Analysis
Customer Reviews
Have you used Anti-5'-3' exoribonuclease 2 XRN2 Antibody?
Submit a review and receive an Amazon gift card.
- $25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Submit A Review
Be the first to review Anti-5'-3' exoribonuclease 2 XRN2 Antibody
*The first user to submit a review for a product is eligible for Boster's Innovating Scientists Reward, which gives product credits. This is in addition to the gift card reward.
Customer Q&As
Have a question?
Find answers in Q&As, reviews.
Can't find your answer?
Submit your question