Anti-5'-3' exoribonuclease 2 XRN2 Antibody

XRN2 antibody

Boster Bio Anti-5'-3' exoribonuclease 2 XRN2 Antibody catalog # A02797-2. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Monkey, Mouse.

Product Info Summary

SKU: A02797-2
Size: 100ul
Reactive Species: Human, Monkey, Mouse
Host: Rabbit
Application: ELISA, IHC, WB

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Product Name

Anti-5'-3' exoribonuclease 2 XRN2 Antibody

View all XRN2 Antibodies

SKU/Catalog Number

A02797-2

Size

100ul

Form

Liquid

Description

Boster Bio Anti-5'-3' exoribonuclease 2 XRN2 Antibody catalog # A02797-2. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Monkey, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-5'-3' exoribonuclease 2 XRN2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02797-2)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human XRN2

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A02797-2 is reactive to XRN2 in Human, Monkey, Mouse

Applications

A02797-2 is guaranteed for ELISA, IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

108.582kDa

Background of XRN2

The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARFof CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARFof CDKN2A By similarity. Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.

Hiroyasu Inada, J. Cell Biol., Oct 2001; 155: 415.
Kenneth M. Izumi, Mol. Cell. Biol., Aug 1999; 19: 5759 - 5767.
Susumu Rokudai, Mol. Cell. Biol., Dec 2002; 22: 8695 - 8708.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000

Validation Images & Assay Conditions

Gene/Protein Information For XRN2 (Source: Uniprot.org, NCBI)

Gene Name

XRN2

Full Name

5'-3' exoribonuclease 2

Weight

108.582kDa

Superfamily

5'-3' exonuclease family

Alternative Names

5'-3' exoribonuclease 2; Dhm1-like protein (mouse homolog); DHM1-like protein; DHP protein; EC 3.1.13; EC 3.1.13.- XRN2 5-3 exoribonuclease 2 5-3 exoribonuclease 2|DHM1-like protein|DHP protein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on XRN2, check out the XRN2 Infographic

XRN2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for XRN2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A02797-2-100ul

100ul

$380

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