Anti-Activin Receptor Type IA (ACVR1) Antibody (N-term)

Activin RIA/ALK-2/Activin Receptor Type 1 antibody

Boster Bio Anti-Activin Receptor Type IA (ACVR1) Antibody (N-term) (Catalog # A00798-3). Tested in WB, IHC-P application(s). This antibody reacts with Human, Rat.

Product Info Summary

SKU: A00798-3
Size: 80 µl
Reactive Species: Human, Rat
Host: Rabbit
Application: IHC-P, WB

Product Name

Anti-Activin Receptor Type IA (ACVR1) Antibody (N-term)

View all Activin RIA/ALK-2/Activin Receptor Type 1 Antibodies

SKU/Catalog Number

A00798-3

Size

80 µl

Description

Boster Bio Anti-Activin Receptor Type IA (ACVR1) Antibody (N-term) (Catalog # A00798-3). Tested in WB, IHC-P application(s). This antibody reacts with Human, Rat.

Storage & Handling

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Cite This Product

Anti-Activin Receptor Type IA (ACVR1) Antibody (N-term) (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00798-3)

Host

Rabbit

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

This Activin Receptor Type IA (ACVR1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human Activin Receptor Type IA (ACVR1).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A00798-3 is reactive to ACVR1 in Human, Rat

Applications

A00798-3 is guaranteed for IHC-P, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

57.153kDa

Background of Activin RIA/ALK-2/Activin Receptor Type 1

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. ACVR1 is an activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:1000
IHC-P: 1:50-1:100

Validation Images & Assay Conditions

Gene/Protein Information For ACVR1 (Source: Uniprot.org, NCBI)

Gene Name

ACVR1

Full Name

Activin receptor type-1

Weight

57.153kDa

Superfamily

protein kinase superfamily

Alternative Names

activin A receptor, type I; Activin RIA; ActivinRIA; ACTRI; ACVR1; ACVR1A; ACVRLK2; ALK2; ALK-2; FOP; SKR1; TSRI ACVR1 ACTRIA, ACVRLK2, ALK2, FOP, SKR1, TSRI, ACVR1 activin A receptor type 1 activin receptor type-1|TGF-B superfamily receptor type I|activin A receptor, type I|activin A receptor, type II-like kinase 2|activin receptor type I|activin receptor-like kinase 2|hydroxyalkyl-protein kinase|serine/threonine-protein kinase receptor R1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ACVR1, check out the ACVR1 Infographic

ACVR1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for ACVR1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Size

Total: $298

SKU:A00798-3

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Lead time for this item is typically 4-6 days

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A00798-3
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$298.00

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