Anti-Adrenergic Receptor alpha-2B ADRA2B Antibody

alpha-2B Adrenergic R/ADRA2B antibody

Boster Bio Anti-Adrenergic Receptor alpha-2B ADRA2B Antibody (Catalog # A03622). Tested in IF applications. This antibody reacts with Human.

Product Info Summary

SKU: A03622
Size: 100 µl
Reactive Species: Human
Host: Rabbit
Application: IF

Product Name

Anti-Adrenergic Receptor alpha-2B ADRA2B Antibody

View all alpha-2B Adrenergic R/ADRA2B Antibodies

SKU/Catalog Number

A03622

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-Adrenergic Receptor alpha-2B ADRA2B Antibody (Catalog # A03622). Tested in IF applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Adrenergic Receptor alpha-2B ADRA2B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03622)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Immunogen

Synthesized peptide derived from internal of human Adrenergic Receptor alpha-2B.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A03622 is reactive to ADRA2B in Human

Applications

A03622 is guaranteed for IF Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

49.954kDa

Background of alpha-2B Adrenergic R/ADRA2B

Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol.

Lomasney J.W., Proc. Natl. Acad. Sci. U.S.A. 87:5094-5098(1990).
Weinshank R.L., Mol. Pharmacol. 38:681-688(1990).
Small K.M., J. Biol. Chem. 276:4917-4922(2001).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunofluorescence: 1:100~1:500

Validation Images & Assay Conditions

Gene/Protein Information For ADRA2B (Source: Uniprot.org, NCBI)

Gene Name

ADRA2B

Full Name

Alpha-2B adrenergic receptor

Weight

49.954kDa

Superfamily

G-protein coupled receptor 1 family

Alternative Names

a-2B AdrenergicR; ADRA2B adrenergic, alpha-2B-, receptor; ADRA2B; ADRA2L1; ADRA2L1adrenergic receptor alpha 2B; ADRA2RL1; ADRARL1; adrenergic, alpha-2B-, receptor; Alpha-2 adrenergic receptor subtype C2; alpha-2-adrenergic receptor-like 1; alpha-2B Adrenergic R; alpha-2B adrenergic receptor; alpha2B AdrenergicR; Alpha-2B adrenoceptor; Alpha-2B adrenoreceptor; alpha-2B-adrenergic receptor; ALPHA2BAR; alpha-2BAR; G-protein coupled receptor ADRA2B ADRA2L1, ADRA2RL1, ADRARL1, ALPHA2BAR, FAME2, alpha-2BAR adrenoceptor alpha 2B alpha-2B adrenergic receptor|ADRA2B adrenergic, alpha-2B-, receptor|G-protein coupled receptor|alpha-2 adrenergic receptor subtype C2|alpha-2-adrenergic receptor-like 1|alpha-2B adrenoreceptor

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ADRA2B, check out the ADRA2B Infographic

ADRA2B infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for ADRA2B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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4 Customer Q&As for Anti-Adrenergic Receptor alpha-2B ADRA2B Antibody

Question

I was wanting to use your anti-Adrenergic Receptor alpha-2B antibody for IF for human apex of heart on frozen tissues, but I want to know if it has been tested for this particular application. Has this antibody been tested and is this antibody a good choice for human apex of heart identification?

Verified Customer

Verified customer

Asked: 2018-10-11

Answer

You can see on the product datasheet, A03622 anti-Adrenergic Receptor alpha-2B antibody has been tested for IF on human tissues. We have an innovator award program that if you test this antibody and show it works in human apex of heart in IHC-frozen, you can get your next antibody for free.

Boster Scientific Support

Answered: 2018-10-11

Question

I see that the anti-Adrenergic Receptor alpha-2B antibody A03622 works with IF, what is the protocol used to produce the result images on the product page?

Verified Customer

Verified customer

Asked: 2017-07-25

Answer

You can find protocols for IF on the "support/technical resources" section of our navigation menu. If you have any further questions, please send an email to [email protected]

Boster Scientific Support

Answered: 2017-07-25

Question

We are currently using anti-Adrenergic Receptor alpha-2B antibody A03622 for human tissue, and we are satisfied with the IF results. The species of reactivity given in the datasheet says human. Is it likely that the antibody can work on canine tissues as well?

R. Evans

Verified customer

Asked: 2015-06-15

Answer

The anti-Adrenergic Receptor alpha-2B antibody (A03622) has not been tested for cross reactivity specifically with canine tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in canine you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2015-06-15

Question

you antibody to test anti-Adrenergic Receptor alpha-2B antibody A03622 on human apex of heart for research purposes, then I may be interested in using anti-Adrenergic Receptor alpha-2B antibody A03622 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?

C. Williams

Verified customer

Asked: 2013-07-18

Answer

The products we sell, including anti-Adrenergic Receptor alpha-2B antibody A03622, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.

Boster Scientific Support

Answered: 2013-07-18

Size

Total: $360

SKU:A03622

Backordered.

Lead time for this item is typically 2-3 weeks

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A03622
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$360.00

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