Anti-Alpha-2B adrenergic receptor ADRA2B Antibody

Product Name

Anti-Alpha-2B adrenergic receptor ADRA2B Antibody

View all alpha-2B Adrenergic R/ADRA2B Antibodies

SKU/Catalog Number

A03622-1

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Alpha-2B adrenergic receptor ADRA2B Antibody catalog # A03622-1. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Alpha-2B adrenergic receptor ADRA2B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03622-1)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human Adrenergic Receptor alpha-2B.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A03622-1 is reactive to ADRA2B in Human, Mouse, Rat

Applications

A03622-1 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

49.954kDa

Background of alpha-2B Adrenergic R/ADRA2B

Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol.

Lomasney J.W., Proc. Natl. Acad. Sci. U.S.A. 87:5094-5098(1990).
Weinshank R.L., Mol. Pharmacol. 38:681-688(1990).
Small K.M., J. Biol. Chem. 276:4917-4922(2001).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000

Validation Images & Assay Conditions

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Figure 1. Western blotting validation for Anti-Alpha-2B adrenergic receptor ADRA2B Antibody A03622-1

Western blot analysis of extracts of various cell lines

Gene/Protein Information For ADRA2B (Source: Uniprot.org, NCBI)

Alternative Names

a-2B AdrenergicR; ADRA2B adrenergic, alpha-2B-, receptor; ADRA2B; ADRA2L1; ADRA2L1adrenergic receptor alpha 2B; ADRA2RL1; ADRARL1; adrenergic, alpha-2B-, receptor; Alpha-2 adrenergic receptor subtype C2; alpha-2-adrenergic receptor-like 1; alpha-2B Adrenergic R; alpha-2B adrenergic receptor; alpha2B AdrenergicR; Alpha-2B adrenoceptor; Alpha-2B adrenoreceptor; alpha-2B-adrenergic receptor; ALPHA2BAR; alpha-2BAR; G-protein coupled receptor ADRA2B ADRA2L1, ADRA2RL1, ADRARL1, ALPHA2BAR, FAME2, alpha-2BAR adrenoceptor alpha 2B alpha-2B adrenergic receptor|ADRA2B adrenergic, alpha-2B-, receptor|G-protein coupled receptor|alpha-2 adrenergic receptor subtype C2|alpha-2-adrenergic receptor-like 1|alpha-2B adrenoreceptor

For more info on ADRA2B, check out the ADRA2B Infographic

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In this infographic, you will see the following information for ADRA2B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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