Anti-BDNF Antibody Picoband™

Boster Bio Anti-BDNF Antibody Picoband™ catalog # PB9075. Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. Cited in 19 publication(s).

Product Info Summary

SKU: PB9075
Size: 100μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: Flow Cytometry, IHC, ICC, WB

Product Name

Anti-BDNF Antibody Picoband™

See all Bdnf products

SKU/Catalog Number

PB9075

Size

100μg/vial

Form

Lyophilized

Description

Boster Bio Anti-BDNF Antibody Picoband™ catalog # PB9075. Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-BDNF Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9075)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Immunogen

Anti-BDNF Picoband™ Antibody (PB9075) was raised against E.coli-derived human BDNF recombinant protein (Position: H129-R247). Human BDNF shares 100% amino acid (aa) sequence identity with both mouse and rat BDNF.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross Reactivity

No cross reactivity with other proteins

Reactive Species

PB9075 is reactive to Bdnf in Human, Mouse, Rat

Applications

PB9075 is guaranteed for Flow Cytometry, IHC, ICC, WB Boster Guarantee

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive your next antibody/ELISA kit free of charge! Applicable to all scientists world wide.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Mouse, Rat, Human, By Heat
Western blot, 0.1-0.5μg/ml, Mouse, Rat, Human
Immunohistochemistry (Frozen Section), 0.5-1μg/ml, Human
Immunocytochemistry, 0.5-1μg/ml, Human
Flow Cytometry, 1-3μg/1x106 cells, Human

Validation Images & Assay Conditions

Gene/Protein Information For Bdnf (Source: Uniprot.Org, NCBI)

Uniprot ID

P21237

Gene ID

12064

Gene Name

Bdnf

Full Name

Brain-derived neurotrophic factor

Weight

28.123kDa

Superfamily

NGF-beta family

Alternative Names

Abrineurin; ANON2; BDNF; brain-derived neurotrophic factor; BULN2; MGC34632; Neurotrophin Bdnf|brain derived neurotrophic factor|brain-derived neurotrophic factor

*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".

For more info on Bdnf, check out the Bdnf Infographic

Bdnf infographic

We have 30,000+ of these available, one for each gene! check them out.

In this infographic you will see the following information for Bdnf: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]

PB9075 has been cited in 19 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Perineurium-like sheath derived from long-term surviving mesenchymal stem cells confers nerve protection to the injured spinal cord
Species: Rat

Xue LL,Du RL,Hu Y,Xiong LL,Su ZY,Ma Z,Tan YX,Liu J,Hu Q,Zhu ZQ,Wang TH,Liu XZ.BDNF promotes neuronal survival after neonatal hypoxic-ischemic encephalopathy by up-regulating Stx1b and suppressing VDAC1.Brain Res Bull.2021 May 28:S0361-9230(21)00144-1.doi:10.1016/j.brainresbull.2021.05.013.Epub ahead of print.PMID:34058286.
Species: Rat
PB9075 usage in article: APP:WB, SAMPLE:CORTEX AND HIPPOCAMPUS, DILUTION:1:100

Fengpei Chen, Shijia Chen, Jie Liu, Nashwa Amin, Weidong Jin, Marong Fang, "Agomelatine Softens Depressive-Like Behavior through the Regulation of Autophagy and Apoptosis", BioMed Research International, vol. 2021, Article ID 6664591, 10 pages, 2021. https://doi.org/10.1155/2021/6664591
Species: Mouse
PB9075 usage in article: APP:WB, SAMPLE:HIPPOCAMPUS TISSUE, DILUTION:1:500

Feng,S.,Wang,S.,Sun,S.,Su,H.,& Zhang,L.(2021).Effects of combination treatment with transcranial magnetic stimulation and bone marrow mesenchymal stem cell transplantation or Raf inhibition on spinal cord injury in rats.Molecular Medicine Reports,23,294.h
Species: Rat
PB9075 usage in article: APP:WB, SAMPLE:SPINAL CORD TISSUE, DILUTION:1:200

Huangqin flavonoid extraction for spinal cord injury in a rat model

Serotonin regulates brain-derived neurotrophic factor expression in select brain regions during acute psychological stress

Beneficial effect of fluoxetine treatment aganist psychological stress is mediated by increasing BDNF expression in selected brain areas

Brain-derived neurotrophic factor is up-regulated in severe acute cauda equina syndrome dog model

Naringenin induces laxative effects by upregulating the expression levels of c-Kit and SCF, as well as those of aquaporin 3 in mice with loperamide-induced constipation

Changes in compressed neurons from dogs with acute and severe cauda equina constrictions following intrathecal injection of brain-derived neurotrophic factor-conjugated polymer nanoparticles

Panax notoginsenoside Rb1 ameliorates Alzheimer?s disease by upregulating brain-derived neurotrophic factor and downregulating Tau protein expression

Acute Stress and Chronic Stress Change Brain-Derived Neurotrophic Factor (BDNF) and Tyrosine Kinase-Coupled Receptor (TrkB) Expression in Both Young and Aged Rat Hippocampus

Effects of Polysaccharide of Gastrodia Elata Blume and Electro-Acupuncture on Expressions of Brain-Derived Neurotrophic Factor and Stem Cell Factor Protein in Caudate Putamen of Focal Cerebral Ischemia Rats

Electroacupuncture Ameliorates Learning and Memory and Improves Synaptic Plasticity via Activation of the PKA/CREB Signaling Pathway in Cerebral Hypoperfusion

Fingolimod induces neurogenesis in adult mouse hippocampus and improves contextual fear memory

Transplantation of human umbilical cord blood mesenchymal stem cells to treat a rat model of traumatic brain injury

Effects of senescence on the expression of BDNF and TrkB receptor in the lateral geniculate nucleus of cats

Li R, Xia W, Zhang Z, Wu K. Plos One. 2011;6(6):E21663. Doi: 10.1371/Journal.Pone.0021663. Epub 2011 Jun 27. S100B Protein, Brain-Derived Neurotrophic Factor, And Glial Cell Line-Derived Neurotrophic Factor In Human Milk.

Li X, Li M, Li Y, Quan Q, Wang J. Neural Regen Res. 2012 Dec 25;7(36):2860-6. Doi: 10.3969/J.Issn.1673-5374.2012.36.002. Cellular And Molecular Mechanisms Underlying The Action Of Ginsenoside Rg1 Against Alzheimer'S Disease.

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1 Customer Q&As for Anti-BDNF Antibody Picoband™

Question

We are currently using anti-BDNF antibody PB9075 for human tissue, and we are satisfied with the ICC results. The species of reactivity given in the datasheet says human, mouse, rat. Is it possible that the antibody can work on goat tissues as well?

Verified Customer

Verified customer

Asked: 2019-07-18

Answer

The anti-BDNF antibody (PB9075) has not been tested for cross reactivity specifically with goat tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in goat you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-07-18

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