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- Table of Contents
BDNF Antibodies
AND BDNF ELISA kits, BDNF Proteins
Many biological assays use antibodies to detect BDNF, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BDNF in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BDNF antibodies...
Designing a Western blot for BDNF? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the BDNF Western Blot GuideBDNF Video by Boster Bio
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All BDNF Products
Product
Figures
Specificity
Applications
Price
Human BDNF PicoKine® Quick ELISA Kit
7 Citations
Human
ELISA
$499
Cat # FEK0307
96 wells/kit, with removable strips.
Cat # FEK0307
96 wells/kit, with removable strips.
Anti-BDNF Rabbit Monoclonal Antibody
12 Citations
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M00035-1
100 μl
Cat # M00035-1
100 μl
Mouse BDNF PicoKine® Quick ELISA Kit
3 Citations
Mouse
ELISA
$499
Cat # FEK0309
96 wells/kit, with removable strips.
Cat # FEK0309
96 wells/kit, with removable strips.
Rat BDNF PicoKine® Quick ELISA Kit
6 Citations
Rat
ELISA
$499
Cat # FEK0308
96 wells/kit, with removable strips.
Cat # FEK0308
96 wells/kit, with removable strips.
Mouse
ELISA
$500
Cat # EZ0309
For 5 plates, 96 wells each, reagents only, plates are not included
Cat # EZ0309
For 5 plates, 96 wells each, reagents only, plates are not included
Rat BDNF ELISA Kit EZ-Set™ (DIY Antibody Pairs)
1 Citations
Rat
ELISA
$500
Cat # EZ0308
For 5 plates, 96 wells each, reagents only, plates are not included
Cat # EZ0308
For 5 plates, 96 wells each, reagents only, plates are not included
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M00035-2
100 μl/vial
Cat # M00035-2
100 μl/vial
Human, Mouse, Rat
IP, IF, IHC, ICC, WB
$370
Cat # P01388
100 μl
Cat # P01388
100 μl
Mouse TrkB ELISA Kit PicoKine®
3 Citations
Mouse
ELISA
$499
Cat # EK0849
96 wells/kit, with removable strips.
Cat # EK0849
96 wells/kit, with removable strips.
Rat TRKB ELISA Kit PicoKine®
1 Citations
Rat
ELISA
$499
Cat # EK1596
96 wells/kit, with removable strips.
Cat # EK1596
96 wells/kit, with removable strips.
Human BDNF Recombinant Protein
1 Citations
SDS-PAGE, Denatured
$250
Cat # PROTP23560
Starting from 20ug
Cat # PROTP23560
Starting from 20ug
Dog Canine BDNF ELISA Kit PicoKine®
1 Citations
Canine
ELISA
$399
Cat # EK0308-CN
96 wells/kit, with removable strips.
Cat # EK0308-CN
96 wells/kit, with removable strips.
Bovine BDNF ELISA Kit PicoKine®
1 Citations
Bovine
ELISA
$399
Cat # EK0307-BV
96 wells/kit, with removable strips.
Cat # EK0307-BV
96 wells/kit, with removable strips.
Human, Mouse, Rat
Cell Culture
$77
Cat # PROTP23560-5
5ug,20ug,100ug
Cat # PROTP23560-5
5ug,20ug,100ug
Rabbit
ELISA
$399
Cat # EK0307-RB
96 wells/kit, with removable strips.
Cat # EK0307-RB
96 wells/kit, with removable strips.
Monkey
ELISA
$399
Cat # EK0307-PR
96 wells/kit, with removable strips.
Cat # EK0307-PR
96 wells/kit, with removable strips.
Pig
ELISA
$399
Cat # EK0307-PO
96 wells/kit, with removable strips.
Cat # EK0307-PO
96 wells/kit, with removable strips.
Equine
ELISA
$399
Cat # EK0307-EQ
96 wells/kit, with removable strips.
Cat # EK0307-EQ
96 wells/kit, with removable strips.
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A01388Y706-1
100ul
Cat # A01388Y706-1
100ul
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A01388Y516
100ul
Cat # A01388Y516
100ul
Human, Mouse, Rat
IP, IF, IHC, ICC, WB
$405
Cat # A01388Y817
100ul
Cat # A01388Y817
100ul
BDNF Overview
Facts about Brain-derived neurotrophic factor.
Brain-derived neurotrophic factor (BDNF)
During development, promotes the survival and differentiation of selected neuronal populations of both peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology.
Major regulator of synaptic transmission and plasticity at adult synapses in several regions of the CNS. The flexibility of BDNF is emphasized by its contribution to a range of adaptive neuronal reactions including long-term potentiation (LTP), long-term depression (LTD), certain kinds of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
Gene Information
| Human | |
|---|---|
| Gene Name: | BDNF |
| Uniprot: | P23560 |
| Entrez: | 627 |
Family
| Belongs to: |
|---|
| NGF-beta family |
Alternative Names
Abrineurin; ANON2; BDNF; brain-derived neurotrophic factor; BULN2; MGC34632; Neurotrophin
Molecular Weight
Mass (kDA):
27.818 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11p14.1 |
| Sequence: | 11; NC_000011.10 (27654893..27722030, complement) |
Tissue Specificity
Brain. Highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. Also expressed in heart, lung, skeletal muscle, testis, prostate and placenta.
Subcellular Localizations
Secreted.; [BDNF precursor form]: Secreted. A proportion of BDNF is secreted as immature precursor (proBDNF).
Diseases
- Depressive Disorder
- Nervousness
- Neurodegenerative Disorders
- Alzheimer's Disease
- Nerve Degeneration
- Schizophrenia
- Major Depressive Disorder
- Stress, Psychological
- Mental Disorders
- Spinal Cord Injuries
- Parkinson Disease
- Anxiety Disorders
- Ischemia
Interacting Proteins
- NTF4
Pathways
- Cell Death
- Regeneration
- Neurogenesis
- Neuroprotection
- Pathogenesis
- Secretion
- Synaptic Transmission
- Localization
- Transport
- Innervation
- Cell Proliferation
- Cognition
- Aging
PTMs
- Phosphorylation
- Cleavage
- Methylation
- Acetylation
- Reduction
- Dephosphorylation
- Oxidation
- Biotinylation
- Iodination
- Glycosylation
Research Areas
- Cytokine Research
- Immunology
- Neuroscience
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BDNF
bosterbio.com/bosterbio-gene-info-cards/BDNF
References
PMID: 2236018 by Jones K.R., et al. Molecular cloning of a human gene that is a member of the nerve growth factor family.
PMID: 1889806 by Maisonpierre P.C., et al. Human and rat brain-derived neurotrophic factor and neurotrophin-3: gene structures, distributions, and chromosomal localizations.
304 Publications of Boster BDNF Antibodies & ELISA Kits
- PubMed ID: 10.4142/jvs.2016.17.1.97, Expression of neurotrophic factors in injured spinal cord after transplantation ...
- PubMed ID: 10.4103/1673-5374.286977, A novel tissue engineered nerve graft constructed with autologous vein and nerve...
- PubMed ID: 10.3969/j.issn.1673-5374.2013.03.005, Changes in compressed neurons from dogs with acute and severe cauda equina const...
- PubMed ID: 10.3892/mmr.2017.7539, Effect of hippocampal L‑NBP on BDNF and TrkB expression and neurological funct...
- PubMed ID: 10.3892/mmr.2017.6851, Resveratrol reversed chronic restraint stress-induced impaired cognitive functio...
- PubMed ID: 10.3760/cma.j.issn.0366-6999.2009.14.008, Study of brain-derived neurotrophic factor gene transgenic neural stem cells in ...
- PubMed ID: 10.3389/fpsyt.2020.00716, Resveratrol, a SIRT1 Activator, Ameliorates MK-801-Induced Cognitive and Motor I...
- PubMed ID: 10.3389/fnbeh.2021.712445, Early Enhancement of Neuroplasticity Index, the Ratio of Serum Brain-Derived Neu...
- PubMed ID: 10.3389/fnbeh.2019.00268, Male C57BL6/N and C57BL6/J Mice Respond Differently to Constant Light and Runnin...
- PubMed ID: 10.3389/fnbeh.2018.00150, Chronic Hippocampal Abnormalities and Blunted HPA Axis in an Animal Model of Rep...
- PubMed ID: 10.3389/fnagi.2020.590530, Long-Term Running Exercise Delays Age-Related Changes in White Matter in Rats
- PubMed ID: 10.3349/ymj.2010.51.5.661, Acute Stress and Chronic Stress Change Brain-Derived Neurotrophic Factor (BDNF) ...
- PubMed ID: 10.3233/THC-199038, Study on the mechanism of TMRK electroacupuncture in repairing synaptic plastici...
- PubMed ID: 10.3233/RNN-150607, Granulocyte-colony stimulating factor promotes brain repair following traumatic ...
- PubMed ID: 10.3233/JAD-180853, Non-Phosphorylated Tau in Cerebrospinal Fluid is a Marker of Alzheimer’s Disea...
- PubMed ID: 10.3233/JAD-160472, Cerebrospinal Fluid Biomarkers in Highly Exposed PM 2.5 Urbanites: The Risk of&n...
- PubMed ID: 10.26355/eurrev_201810_16057, Research on changes in cognitive function, β-amyloid peptide and neurotrophic f...
- PubMed ID: 10.22038/ijbms.2019.29012.7002, Centella asiatica (Gotu kola) ethanol extract up-regulates hippocampal brain-der...
- PubMed ID: 10.2174/1566523218666180413150023, Transplantation of BDNF Gene Recombinant Mesenchymal Stem Cells and Adhesive Pep...
- PubMed ID: 10.2147/TCRM.S182325, The expressions of NGF and VEGF in the fracture tissues are closely associated w...
- PubMed ID: 10.2147/NDT.S289444, Berberine Suppresses Mice Depression Behaviors and Promotes Hippocampal Neurons ...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page