Anti-C-C motif chemokine 4 CCL4 Antibody

Product Name

Anti-C-C motif chemokine 4 CCL4 Antibody

View all CCL4 Antibodies

SKU/Catalog Number

A00703

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-C-C motif chemokine 4 CCL4 Antibody (Catalog # A00703). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

CCL4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-C-C motif chemokine 4 CCL4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00703)

Host

Rabbit

Contents

CCL4 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Rabbit polyclonal CCL4 antibody was raised against a 15 amino acid peptide near the center of human CCL4. The immunogen is located within the first 50 amino acids of CCL4.

Reactive Species

A00703 is reactive to CCL4 in Human, Mouse, Rat

Observed Molecular Weight

68 kDa

Calculated molecular weight

10.2 kDa

Background of CCL4

CCL4, also known as macrophage inflammatory protein 1-beta (MIP1B), belongs to the intercrine beta (chemokine CC) family. Both CCL4 and the related protein CCL3 participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells. While both CCL4 and CCL3 exert similar effects on monocytes, their effect on lymphocytes differ; with CCL4 selectively attracting CD4+ lymphocytes and CCL3 selectively attracting CD8+ lymphocytes. Additionally, both have been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. The processed form of CCL4 can induce down-modulation of surface expression of the chemokine receptor CCR5, thus inhibiting the CCR5-mediated entry of HIV-1 in T cells.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Applications

A00703 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

CCL4 antibody can be used for detection of CCL4 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information CCL4

Here are featured tools and databases that you might find useful.

• Boster's Pathways Library
• Protein Databases
• Bioscience Research Protocol Resources
• Data Processing & Analysis Software
• Photo Editing Software
• Scientific Literature Resources
• Research Paper Management Tools
• Molecular Biology Software
• Primer Design Tools
• Bioinformatics Tools
• Phylogenetic Tree Analysis