Anti-CFTR Antibody

CFTR antibody

Boster Bio Anti-CFTR Antibody (Catalog # A00028). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A00028
Size: 0.1 mg
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, IF, IHC-P, WB

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Product Name

Anti-CFTR Antibody

View all CFTR Antibodies

SKU/Catalog Number

A00028

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-CFTR Antibody (Catalog # A00028). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

CFTR antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-CFTR Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00028)

Host

Rabbit

Contents

CFTR Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

SK7

Isotype

IgG

Immunogen

CFTR antibody was raised against an 18 amino acid peptide near the carboxy terminus of human CFTR. The immunogen is located within amino acids 1290 - 1340 of CFTR.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

CFTR antibody is human, mouse and rat reactive.

Reactive Species

A00028 is reactive to CFTR in Human, Mouse, Rat

Applications

A00028 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

168.142kDa

Background of CFTR

The cystic fibrosis transmembrane conductance regulator (CFTR) protein is a member of the ATP-binding cassette (ABC) transporter superfamily, and a member of the MRP subfamily that is involved in multi-drug resistance (1,2). CFTR functions as a chloride channel and controls the regulation of other transport pathways (3). Mutations in this gene are associated with the autosomal recessive disorder cystic fibrosis, the most common, fatal, inherited disease of caucasian populations (1).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

CFTR antibody can be used for detection of CFTR by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For CFTR (Source: Uniprot.org, NCBI)

Gene Name

CFTR

Full Name

Cystic fibrosis transmembrane conductance regulator

Weight

168.142kDa

Superfamily

ABC transporter superfamily

Alternative Names

ABC35; ABCC7CF; ATP-binding cassette sub-family C member 7; ATP-binding cassette transporter sub-family C member 7; cAMP-dependent chloride channel; CFTR; CFTR/MRP; Channel conductance-controlling ATPase; cystic fibrosis transmembrane conductance regulator (ATP-binding cassettesub-family C, member 7); cystic fibrosis transmembrane conductance regulator; cystic fibrosis transmembrane conductance regulator, ATP-binding cassette(sub-family C, member 7); dJ760C5.1; EC 3.6.3; MRP7EC 3.6.3.49; TNR-CFTR CFTR ABC35, ABCC7, CF/MRP, MRP7, TNR-CFTR, dJ760C5.1, CFTR CF transmembrane conductance regulator cystic fibrosis transmembrane conductance regulator|cAMP-dependent chloride channel|channel conductance-controlling ATPase|cystic fibrosis transmembrane conductance regulating|cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CFTR, check out the CFTR Infographic

CFTR infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CFTR: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A00028-0.1 mg

0.1 mg

$449

Free Secondary Antibody

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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
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