Anti-Cytokeratin Peptide 7 KRT7 Antibody (Monoclonal, LDS-68)
Mouse IgG monoclonal antibody for Cytokeratin Peptide 7, keratin 7 (KRT7) detection. Tested with WB, IHC-P, IHC-F in Human. No cross reactivity with other proteins. Cited in 2 publication(s).
Anti-Cytokeratin Peptide 7 KRT7 Antibody (Monoclonal, LDS-68) Info At A Glance
|Product Name||Anti-Cytokeratin Peptide 7 KRT7 Antibody (Monoclonal, LDS-68)
See all Krt7 primary antibodies, ELISA kits and proteins
|Storage & Handling||At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.|
|Description||Monoclonal clone# G2 antibody for CYTOKERATIN 7/KRT7 detection. Host: Mouse.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. CYTOKERATIN 7/KRT7 information: Molecular Weight: 50709 MW; Subcellular Localization: KRT7: Cytoplasm; Tissue Specificity: KRT7: Expressed in cultured epidermal, bronchial andmesothelial cells but absent in colon, ectocervix and liver.Observed throughout the glandular cells in the junction betweenstomach and esophagus but is absent in the esophagus.|
|Cite This Product||Anti-Cytokeratin Peptide 7 KRT7 Antibody (Monoclonal, LDS-68) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1024)|
|Similar Products From
|Anti-Cytokeratin Peptide 7 KRT7 Antibody (Monoclonal, LDS-68) may replace the following items: sc 17116|sc 17118|sc 23876|sc 25721|sc 51585|sc 53263|sc 53264|sc 53265|sc 70936|sc 8421.|
*Our Boster Guarantee covers the use of this product in the above tested applications.
*Innovating Scientists reward: if you test this antibody on a species or application not listed above and share with us your results, we will provide you a full credit to purchase Boster products.
|Related Products||Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P) and IHC(F).
*Blocking peptide can be purchased at $50. Contact us for more information.
**Boster also offers various secondary antibodies for Immunoflourescecne and IHC. Take advantage of the buy 1 primary antibody get 1 secondary antibody for free promotion all year round.
|Immunogen||Cytoskeletal preparation of the RT4 human bladder carcinoma cell line.|
|Cross Reactivity||No cross reactivity with other proteins|
Gene/Protein Basic Information For KRT7 (Source: Uniprot.org, NCBI)
|NCBI Gene Id||300242|
|Species Of This Entry||Rat|
|Protein Name||Keratin, type II cytoskeletal 7|
|Superfamily||intermediate filament family|
|Alternative Names||Krt7|CK7; CK-7; cytokeratin 7; cytokeratin-7; K2C7; K7keratin, 55K type II cytoskeletal; keratin 7; keratin, type II cytoskeletal 7; keratin-7; MGC129731; MGC3625; sarcolectin; SCLkeratin, simple epithelial type I, K7; type II mesothelial keratin K7; Type-II keratin Kb7|
|Post Tranlational Modifications||Methylation; Glycosylation; Cleavage|
|Gene Location||7q36, on Chromasome 7, gene sequence:|
*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".
Ontology For KRT7 (Source: Uniprot.org, NCBI)
|Protein Function||Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. .|
|Research Areas||Cell Biology; Cellular Markers|
|Related Diseases||Neoplasms; Carcinoma; Adenocarcinoma; Malignant Neoplasms; Neoplasm Metastasis; Malignant Paraganglionic Neoplasm; Lung Neoplasms; Ovarian Neoplasm; Metaplasia; Mucinous Adenocarcinoma; Kidney Neoplasm; Carcinoma, Transitional Cell; Liver Neoplasms; Renal Cell Carcinoma; Colonic Neoplasms; Cell Invasion; Mammary Neoplasms; Colorectal Neoplasms; Bladder Neoplasm|
|Related Pathways||Localization; Regeneration; Pathogenesis; Cell Proliferation; Cell Adhesion; Mismatch Repair; Translation; Cell Cycle; Cell Differentiation; Transdifferentiation; Dedifferentiation; Keratinization; Cell Activation; Cell Motility; Liver Regeneration; Secretion; Transport; Cell Migration; Vasculogenesis|
|Background||KRT7 is a type II keratin of simple nonkeratinizing epithelia. The deduced 489-amino acid protein has a calculated molecular mass of about 54 kD. K7 contains 4 central alpha-helical segments with heptad repeats of hydrophobic residues characteristic of a coiled-coil region. Within this domain, K7 shares 73% homology with epidermal K6B. KRT7 gene contains 9 exons and spans more than 15.6 kb. K7 gene is mapped to chromosome 12. Keratin 7 is expressed in a wide range of epithelial structures in humans.|
|Scientific References||PMID: 15085952 by Hesse M., et al. Comprehensive analysis of keratin gene clusters in humans and rodents.|
Our Boster Quality Guarantee for Anti-Cytokeratin Peptide 7 KRT7 Antibody (Monoclonal, LDS-68) covers its use in the following applications.Immunohistochemistry(Paraffin-embedded Section), 2-4μg/ml, Human, By Heat
Immunohistochemistry(Frozen Section), 2-4μg/ml, Human, -
Western blot, 1-2μg/ml, Human
*The recommended dilution ratios/concentrations are for reference only and optimal dilutions/concentrations should be determined by the end user.
Boster provides comprehensive technical information for WB, IHC/IF/ICC, Flow Cytometry sample preparation protocols, assay protocols, troubleshooting tips and assay optimization tips.
- Western Blottting Resource Center
- Immunohistochemistry Resource Center
- Flow Cytometry Technical Resource Center
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Total number of citations: 2
|Bu S, Zhang Q, Wang Q, Lai D. Int J Oncol. 2017 Nov;51(5):1405-1414. doi: 10.3892/ijo.2017.4123. Epub 2017 Sep 14. Human amniotic epithelial cells inhibit growth of epithelial ovarian cancer cells via TGF-β1-mediated cell cycle arrest||PubMed ID 29048644|
|EPHB4 regulates human trophoblast cell line HTR-8/SVneo function: implications for the role of EPHB4 in preeclampsia||PubMed ID 27512150|
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