Product Info Summary
SKU: | A03790-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | Flow Cytometry, IP, IF, IHC, ICC, WB |
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Product info
Product Name
Anti-Diablo homolog, mitochondrial DIABLO Antibody
View all SMAC/Diablo Antibodies
SKU/Catalog Number
A03790-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Diablo homolog, mitochondrial DIABLO Antibody catalog # A03790-1. Tested in WB,ICC/IF,IHC,IP,Flow Cytometry applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Diablo homolog, mitochondrial DIABLO Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03790-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Mnk1 around the phosphorylation site of T385.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A03790-1 is reactive to DIABLO in Human, Mouse, Rat
Applications
A03790-1 is guaranteed for Flow Cytometry, IP, IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
27.131kDa
Background of SMAC/Diablo
May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.
Fukunaga R., EMBO J. 16:1921-1933(1997).
Knauf U., Mol. Cell. Biol. 21:5500-5511(2001).
O'Loghlen A., Exp. Cell Res. 299:343-355(2004).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1,000-1:2,000
ICC: 1:50-1:200
IHC: 1:50-1:200
FC: 1:50-1:100
Validation Images & Assay Conditions
Click image to see more details
Figure 2. Immunocytochemistry staining of DIABLO using Anti-Diablo homolog
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Figure 1. Western blotting validation for Anti-Diablo homolog
Protein Target Info & Infographic
Gene/Protein Information For DIABLO (Source: Uniprot.org, NCBI)
Gene Name
DIABLO
Full Name
Diablo homolog, mitochondrial
Weight
27.131kDa
Alternative Names
0610041G12Rik; Diablo; diablo, IAP-binding mitochondrial protein; Direct IAP-binding protein with low pI; mitochondrial Smac protein; Second mitochondria-derived activator of caspase; SMAC; SMACmitochondrial DIABLO DFNA64, SMAC diablo IAP-binding mitochondrial protein diablo homolog, mitochondrial|diablo-like protein|direct IAP-binding protein with low pI|second mitochondria-derived activator of caspase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on DIABLO, check out the DIABLO Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for DIABLO: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Diablo homolog, mitochondrial DIABLO Antibody (A03790-1)
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No publications found for A03790-1
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