Anti-DUT Antibody

dUTPase antibody

Boster Bio Anti-DUT Antibody catalog # PA1030-1. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: PA1030-1
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IHC, WB

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Product Name

Anti-DUT Antibody

View all dUTPase Antibodies

SKU/Catalog Number



100 μg/vial




Boster Bio Anti-DUT Antibody catalog # PA1030-1. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-DUT Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1030-1)




Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.




Rabbit IgG


A synthetic peptide corresponding to a sequence at the C-terminus of human DUT (212-229aa KKGDRIAQLICERIFYPE), different from the related rat and mouse sequences by two amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.


No cross-reactivity with other proteins

Reactive Species

PA1030-1 is reactive to DUT in Human, Mouse, Rat


PA1030-1 is guaranteed for IHC, WB Boster Guarantee

Background of dUTPase

Deoxyuridine triphosphate nucleotidohydrolase (dUTPase) is responsible for maintaining low intracellular levels of dUTP, thus preventing the incorporation of dUTP into DNA. dUTPase activity/expression can be down-regulated using siRNA specifically targeted to dUTPase mRNA and dUTPase plays a role in DNA nucleotide metabolism. This protein, present predominantly in the cytoplasm, contains 252 amino acids with a Mr of 26,704. It exhibits 35% identity with the E.coli dUTPase and 53% identity with the Saccharomyces cerevisiae enzyme. The nuclear and mitochondrial forms of dUTPase are encoded by the same gene with isoform-specific transcripts arising through the use of alternative 5-prime exons. Human dUTPase exhibits 92% identity with rat. Moreover, this enzyme has profound effects on the efficacy of agents that target thymidylate biosynthesis.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Rat, Mouse, By Heat
Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat

Validation Images & Assay Conditions

Gene/Protein Information For DUT (Source:, NCBI)

Uniprot ID


Gene ID


Gene Name


Full Name

Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial




dUTPase family

Alternative Names

deoxyuridine triphosphatase; dUTP pyrophosphatasedUTP nucleotidohydrolase; dUTPasedeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial; EC; FLJ20622 DUT dUTPase deoxyuridine triphosphatase deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial|dUTP diphosphatase|dUTP nucleotidohydrolase|dUTP pyrophosphatase

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on DUT, check out the DUT Infographic

DUT infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for DUT: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]

No publications found for PA1030-1

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7 Customer Q&As for Anti-DUT Antibody


We are currently using anti-DUT antibody PA1030-1 for human tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it true that the antibody can work on canine tissues as well?

Verified Customer

Verified customer

Asked: 2020-04-07


The anti-DUT antibody (PA1030-1) has not been tested for cross reactivity specifically with canine tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in canine you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2020-04-07


I see that the anti-DUT antibody PA1030-1 works with IHC, what is the protocol used to produce the result images on the product page?

Verified Customer

Verified customer

Asked: 2019-12-17


You can find protocols for IHC on the "support/technical resources" section of our navigation menu. If you have any further questions, please send an email to [email protected]

Boster Scientific Support

Answered: 2019-12-17


I was wanting to use your anti-DUT antibody for IHC for human brain on frozen tissues, but I want to know if it has been tested for this particular application. Has this antibody been tested and is this antibody a good choice for human brain identification?

N. Collins

Verified customer

Asked: 2019-07-23


You can see on the product datasheet, PA1030-1 anti-DUT antibody has been tested for IHC, WB on human, mouse, rat tissues. We have an innovator award program that if you test this antibody and show it works in human brain in IHC-frozen, you can get your next antibody for free.

Boster Scientific Support

Answered: 2019-07-23


We want to test anti-DUT antibody PA1030-1 on human brain for research purposes, then I may be interested in using anti-DUT antibody PA1030-1 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?

Verified Customer

Verified customer

Asked: 2019-03-27


The products we sell, including anti-DUT antibody PA1030-1, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.

Boster Scientific Support

Answered: 2019-03-27


Is there a BSA free version of anti-DUT antibody PA1030-1 available?

K. Li

Verified customer

Asked: 2017-05-29


Thanks for your recent telephone inquiry. I can confirm that some lots of this anti-DUT antibody PA1030-1 are BSA free. For now, these lots are available and we can make a BSA free formula for you free of charge. It will take 3 extra days to prepare. If you require this antibody BSA free again in future, please do not hesitate to contact me and I will be pleased to check which lots we have in stock that are BSA free.

Boster Scientific Support

Answered: 2017-05-29


Will PA1030-1 anti-DUT antibody work on parafin embedded sections? If so, which fixation method do you recommend we use (PFA, paraformaldehyde, other)?

Z. Parker

Verified customer

Asked: 2016-04-29


It shows on the product datasheet, PA1030-1 anti-DUT antibody as been validated on IHC. It is best to use PFA for fixation because it has better tissue penetration ability. PFA needs to be prepared fresh before use. Long term stored PFA turns into formalin, as the PFA molecules congregate and become formalin.

Boster Scientific Support

Answered: 2016-04-29


I appreciate helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for brain using anti-DUT antibody PA1030-1. Let me know if you need anything else.

M. Zhao

Verified customer

Asked: 2015-09-22


Thanks for the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2015-09-22



Total: $315


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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)

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