Anti-Kallikrein 1/KLK1 Antibody

Kallikrein 1 antibody

Boster Bio Anti-Kallikrein 1/KLK1 Antibody catalog # PA1709. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat. Cited in 4 publication(s).

Product Info Summary

SKU: PA1709
Size: 100 μg/vial
Reactive Species: Mouse, Rat
Host: Rabbit
Application: IHC, WB

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Product Name

Anti-Kallikrein 1/KLK1 Antibody

View all Kallikrein 1 Antibodies

SKU/Catalog Number

PA1709

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Kallikrein 1/KLK1 Antibody catalog # PA1709. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Kallikrein 1/KLK1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1709)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of mouse Kallikrein 1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1709 is reactive to KLK1 in Mouse, Rat

Applications

PA1709 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

29 kDa

Calculated molecular weight

28.89kDa

Background of Kallikrein 1

KLK1 (KALLIKREIN 1), also called KLKR, is a protein that in humans is encoded by the KLK1 gene. KLK1 is a member of the peptidase S1 family. KLK1 is a serine protease that generates Lys-bradykinin by specific proteolysis of kininogen-1. The KLK1 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19 and its exact cytogenetic location is 19q13.33. The KLK1 gene contains 5 coding exons. And KLK1 is the most centromeric gene in the cluster. Mice lacking tissue kallikrein are unable to generate significant levels of kinins in most tissues and develop cardiovascular abnormalities early in adulthood despite normal blood pressure. The protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Mouse, By Heat
Western blot, 0.1-0.5μg/ml, Mouse, Rat

Validation Images & Assay Conditions

Gene/Protein Information For KLK1 (Source: Uniprot.org, NCBI)

Gene Name

KLK1

Full Name

Kallikrein-1

Weight

28.89kDa

Superfamily

peptidase S1 family

Alternative Names

EC 3.4.21; EC 3.4.21.35; glandular kallikrein 1; hK1; Kallikrein 1; kallikrein 1, renal/pancreas/salivary; kallikrein serine protease 1; kallikrein-1; Kidney/pancreas/salivary gland kallikrein; KLK1; Klk6; KLKR; Tissue kallikrein KLK1 KLKR, Klk6, hK1 kallikrein 1 kallikrein-1|glandular kallikrein 1|kallikrein 1, renal/pancreas/salivary|kallikrein serine protease 1|kidney/pancreas/salivary gland kallikrein|tissue kallikrein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on KLK1, check out the KLK1 Infographic

KLK1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for KLK1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

PA1709 has been cited in 4 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Dynamic involvement of ATG5 in cellular stress responses

Tracing tumorigenesis in a solid tumor model at single-cell resolution
Species: Mouse

The Goblet Cell Protein Clca1 (Alias mClca3 or Gob-5) Is Not Required for Intestinal Mucus Synthesis, Structure and Barrier Function in Naive or DSS-Challenged Mice

Dynamic involvement of ATG5 in cellular stress responses

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Order DetailsPrice
PA1709

100μg

$370
PA1709-10ug

10μg sample (liquid)

$99
PA1709-Biotin

100 μg Biotin conjugated

$570
PA1709-Cy3

100 μg Cy3 conjugated

$570
PA1709-Dylight488

100 μg Dylight488 conjugated

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PA1709-Dylight550

100 μg Dylight550 conjugated

$570
PA1709-Dylight594

100 μg Dylight594 conjugated

$570
PA1709-FITC

100 μg FITC conjugated

$570
PA1709-HRP

100 μg HRP conjugated

$570
PA1709-APC

100 μg APC conjugated

$670
PA1709-PE

100 μg PE conjugated

$670
PA1709-carrier-free

Carrier Free

$370

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