Product Info Summary
SKU: | A06163-2 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IHC, WB |
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Product info
Product Name
Anti-mGluR-6 (A865) GRM6 Antibody
SKU/Catalog Number
A06163-2
Size
100ul
Form
Liquid
Description
Boster Bio Anti-mGluR-6 (A865) GRM6 Antibody catalog # A06163-2. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-mGluR-6 (A865) GRM6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06163-2)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human GluR6.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A06163-2 is reactive to GRM6 in Human, Mouse, Rat
Applications
A06163-2 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
95.468kDa
Background of mGluR6
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity By similarity. Signaling stimulates TRPM1 channel activity and Ca2+ uptake. Required for normal vision.
Inga Everts, J. Neurosci., Feb 1999; 19: 916.
Gregory D. Salinas, J. Biol. Chem., Dec 2006; 281: 40164 - 40173.
Sheng Yan, J. Neurosci., Jan 2004; 24: 679.
Xiao-Mei Liu, J. Biol. Chem., Jun 2006; 281: 17432 - 17445.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Reconsitution
Restore with deionized water (or equivalent) for reconstitution volume of 100 µL
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
IHC: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 2. Immunohistochemistry validation of GRM6 using Anti-mGluR-6 (A865) GRM6 Antibody (A06163-2).
Immunohistochemistry (IHC) analyzes of mGluR-6 (A865) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.For more protocol information of IHC
Click image to see more details
Figure 1. Western blotting validation for Anti-mGluR-6 (A865) GRM6 Antibody A06163-2
Western blot (WB) analysis of mGluR-6 (A865) polyclonal antibody at 1:500 dilutionLane1:Hela cell lysate
Lane2:NIH-3T3 cell lysate
Lane3:Raw264.7 cell lysate
Lane4:H9C2 cell lysate
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For GRM6 (Source: Uniprot.org, NCBI)
Gene Name
GRM6
Full Name
Metabotropic glutamate receptor 6
Weight
95.468kDa
Superfamily
G-protein coupled receptor 3 family
Alternative Names
CSNB1B; glutamate receptor, metabotropic 6; Gm3; GPRC1F; GPRC1Fmetabotropic glutamate receptor 6; GRM6; mGlu6; mGluR6; MGLUR6DKFZp686H1993 GRM6 CSNB1B, GPRC1F, MGLUR6, mGlu6 glutamate metabotropic receptor 6 metabotropic glutamate receptor 6|glutamate receptor, metabotropic 6
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GRM6, check out the GRM6 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GRM6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-mGluR-6 (A865) GRM6 Antibody (A06163-2)
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No publications found for A06163-2
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