Anti-MOF KAT8 Monoclonal Antibody

Product Name

Anti-MOF KAT8 Monoclonal Antibody

View all MYST1 Antibodies

SKU/Catalog Number

A02757

Size

100μl

Form

Liquid

Description

Boster Bio Anti-MOF KAT8 Monoclonal Antibody catalog # A02757. Tested in IF, IHC-P, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-MOF KAT8 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02757)

Host

Mouse

Contents

Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.

Clonality

Monoclonal

Clone Number

8C4C4

Isotype

IgG

Immunogen

Purified recombinant fragment of human MOF expressed in E. Coli.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A02757 is reactive to Kat8 in Human

Applications

A02757 is guaranteed for IF, IHC-P, WB Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

52.574kDa

Background of MYST1

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of a-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Emamian ES, et al. (2004) J Neurosci. 24(7): 1561-4
Palmer, C.L. et al. (2005) Pharmacol. Rev. 57, 253-277.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000
IHC, 1:200-1:1000
IF, 1:200-1:1000

Validation Images & Assay Conditions

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Western Blot (WB) analysis using MOF Monoclonal antibody against HeLa (1), HepG2 (2) and SMMC-7721 (3) cell lysate.

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Immunohistochemistry (IHC) analysis of paraffin-embedded human esophageal squamous cell carcinoma (A), normal esophagus epithelium (B), rectum adenocarcinoma (C), lung squamous cell carcinoma (D), breast infiltrating carcinoma (E), and breast infiltrating carci.

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Confocal Immunofluorescence (IF) analysis of Eca 109 cells using MOF Monoclonal antibody (green), showing nuclear localization.

Gene/Protein Information For Kat8 (Source: Uniprot.org, NCBI)

Alternative Names

FLJ14040; hMOFhistone acetyltransferase MYST1; KAT8; MOFEC 2.3.1.48; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1; MYST histone acetyltransferase 1; MYST-1; ortholog of Drosophila males absent on the first (MOF); probable histone acetyltransferase MYST1 Kat8|2010203C02Rik, 5830450F21Rik, D7Ertd629, D7Ertd629e, MO, MOF, MYST-1, Myst, Myst1|K(lysine) acetyltransferase 8|histone acetyltransferase KAT8|MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1|MYST histone acetyltransferase 1|histone acetyltransferase Myst1|lysine acetyltransferase 8|probable histone acetyltransferase MYST1

For more info on Kat8, check out the Kat8 Infographic

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In this infographic, you will see the following information for Kat8: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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