Anti-MST-3 STK24 Antibody

MST3 antibody

Boster Bio Anti-MST-3 STK24 Antibody catalog # A04112-2. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A04112-2
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, IHC, WB

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Product Name

Anti-MST-3 STK24 Antibody

View all MST3 Antibodies

SKU/Catalog Number

A04112-2

Size

100ul

Form

Liquid

Description

Boster Bio Anti-MST-3 STK24 Antibody catalog # A04112-2. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-MST-3 STK24 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04112-2)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human MST-3

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A04112-2 is reactive to STK24 in Human, Mouse, Rat

Applications

A04112-2 is guaranteed for ELISA, IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

49.308kDa

Background of MST3

Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr-442' and stimulates its kinase activity. Regulates cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12. May act as a key regulator of axon regeneration in the optic nerve and radial nerve.

Schinkmann K., J. Biol. Chem. 272:28695-28703(1997).
Zhou T.-H., J. Biol. Chem. 275:2513-2519(2000).
Dunham A., Nature 428:522-528(2004).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000

Validation Images & Assay Conditions

Gene/Protein Information For STK24 (Source: Uniprot.org, NCBI)

Gene Name

STK24

Full Name

Serine/threonine-protein kinase 24

Weight

49.308kDa

Superfamily

protein kinase superfamily

Alternative Names

EC 2.7.11; EC 2.7.11.1; Mammalian STE20-like protein kinase 3; MST-3; MST3serine/threonine kinase 24 (Ste20, yeast homolog); serine/threonine kinase 24; serine/threonine-protein kinase 24; STE20; STE20-like kinase 3; STE20-like kinase MST3; sterile 20-like kinase 3; STK3yeast) STK24 HEL-S-95, MST3, MST3B, STE20, STK3 serine/threonine kinase 24 serine/threonine-protein kinase 24|STE20-like kinase 3|STE20-like kinase MST3|epididymis secretory protein Li 95|mammalian STE20-like protein kinase 3|serine/threonine kinase 24 (STE20 homolog, yeast)|sterile 20-like kinase 3

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on STK24, check out the STK24 Infographic

STK24 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for STK24: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A04112-2-100ul

100ul

$380

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