Anti-Mucin Gastric MUC5AC Antibody (Monoclonal, 45M1)

MUC5AC antibody

Boster Bio Anti-Mucin Gastric MUC5AC Antibody (Monoclonal, 45M1) catalog # MA1061. Tested in IHC, ICC, WB applications. This antibody reacts with Human, Rabbit, Rat. Cited in 2 publication(s).

Product Info Summary

SKU: MA1061
Size: 100μg/vial
Reactive Species: Human, Rabbit, Rat
Host: Mouse
Application: IHC, ICC, WB

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Product Name

Anti-Mucin Gastric MUC5AC Antibody (Monoclonal, 45M1)

View all MUC5AC Antibodies

SKU/Catalog Number

MA1061

Size

100μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Mucin Gastric MUC5AC Antibody (Monoclonal, 45M1) catalog # MA1061. Tested in IHC, ICC, WB applications. This antibody reacts with Human, Rabbit, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Mucin Gastric MUC5AC Antibody (Monoclonal, 45M1) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1061)

Host

Mouse

Contents

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Clonality

Monoclonal

Clone Number

45M1

Isotype

Mouse IgG1

Immunogen

Mucin from human ovarian cyst fluid.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross Reactivity

No cross reactivity with other proteins

Reactive Species

MA1061 is reactive to MUC5AC in Human, Rabbit, Rat

Applications

MA1061 is guaranteed for IHC, ICC, WB Boster Guarantee

Background of MUC5AC

Mucin 5AC  (Muc5AC) is a protein that in humans is encoded by the MUC5AC gene. Using real-time RT-PCR, Moehle et al.  (2006) found that MUC5AC was highly expressed in adult trachea and stomach. Expression was lower in adult lung and weak in fetal lung, and no expression was detected in other tissues. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease. Moreover, Muc5ac is identified as a direct and critical mediator of resistance during intestinal nematode infection.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Reconsitution

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 2-4μg/ml, Human, rabbit, rat, By Heat
Immunocytochemistry , 1μg/ml, Human, rabbit, rat, -
Western blot, 1-2μg/ml, Human, rabbit, rat

Validation Images & Assay Conditions

Gene/Protein Information For MUC5AC (Source: Uniprot.Org, NCBI)

Uniprot ID

P98088

Gene ID

4586

Gene Name

MUC5AC

Full Name

Mucin-5AC

Weight

585.57kDa

Alternative Names

gastric mucin; leB; lewis B blood group antigen; major airway glycoprotein; MUC5; mucin 5, subtypes A and C, tracheobronchial/gastric; mucin 5AC, oligomeric mucus/gel-forming pseudogene; mucin 5AC, oligomeric mucus/gel-forming; mucin-5 subtype AC, tracheobronchial; mucin-5AC; TBM; tracheobronchial mucin MUC5AC MUC5, TBM, leB, mucin mucin 5AC, oligomeric mucus/gel-forming mucin-5AC|gastric mucin|lewis B blood group antigen|major airway glycoprotein|mucin 5, subtypes A and C, tracheobronchial/gastric|mucin 5AC, oligomeric mucus/gel-forming pseudogene|mucin-5 subtype AC, tracheobronchial|tracheobronchial mucin

*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".

For more info on MUC5AC, check out the MUC5AC Infographic

MUC5AC infographic

We have 30,000+ of these available, one for each gene! check them out.

In this infographic you will see the following information for MUC5AC: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]

MA1061 has been cited in 2 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Huang J,Liu J,Chang G,Wang Y,Ma N,Roy AC,Shen X.Glutamine Supplementation Attenuates the Inflammation Caused by LPS-Induced Acute Lung Injury in Mice by Regulating the TLR4/MAPK Signaling Pathway.Inflammation.2021 Jun 23.doi:10.1007/s10753-021-01491-2.Epub ahead of print.PMID:34160729.
Species: Mouse
MA1061 usage in article: APP:WB, SAMPLE:LUNG TISSUE, DILUTION:1:1000

Zhou J, Perelman Jm, Kolosov Vp, Zhou X. Mol Cell Biochem. 2013 May;377(1-2):75-85. Doi: 10.1007/S11010-013-1572-3. Epub 2013 Feb 8. Neutrophil Elastase Induces Muc5Ac Secretion Via Protease-Activated Receptor 2.

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1 Customer Q&As for Anti-Mucin Gastric MUC5AC Antibody (Monoclonal, 45M1)

Question

We are currently using anti-Mucin Gastric antibody (Monoclonal, 45M1) MA1061 for rabbit tissue, and we are satisfied with the ICC results. The species of reactivity given in the datasheet says human, rabbit, rat. Is it true that the antibody can work on zebrafish tissues as well?

J. Kulkarni

Verified customer

Asked: 2014-07-14

Answer

The anti-Mucin Gastric antibody (Monoclonal, 45M1) (MA1061) has not been validated for cross reactivity specifically with zebrafish tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in zebrafish you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2014-07-14

Size

Total: $315

SKU:MA1061

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MA1061
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$315.00

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