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- Table of Contents
Mucin-5AC Antibodies
AND MUC5AC ELISA kits, Mucin-5AC Proteins
Many biological assays use antibodies to detect Mucin-5AC, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Mucin-5AC in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Mucin-5AC antibodies...
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MUC5AC Infographic by Boster Bio
All MUC5AC Products
Product
Figures
Specificity
Applications
Price
Anti-Mucin Gastric MUC5AC Antibody (Monoclonal, 45M1)
2 Citations 1 Q&As
Human, Rabbit, Rat
IHC, ICC, WB
$370
Cat # MA1061
100 μg/vial
Cat # MA1061
100 μg/vial
Anti-Mucin 5AC/MUC5AC Antibody Picoband®
3 Citations 16 Q&As
Human
IHC, WB
$370
Cat # PA2303
100 μg/vial
Cat # PA2303
100 μg/vial
Anti-MUC5AC/Mucin 5Ac Rabbit Monoclonal Antibody
1 Citations 16 Q&As
Human
IF, IHC, ICC, WB
$370
Cat # M00612-1
100 μl
Cat # M00612-1
100 μl
MUC5AC Overview
Facts about Mucin-5AC.
Mucin-5AC (MUC5AC)
Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are then removed by the mucocilary system. .
Gene Information
| Human | |
|---|---|
| Gene Name: | MUC5AC |
| Uniprot: | P98088 |
| Entrez: | 4586 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
gastric mucin; leB; lewis B blood group antigen; major airway glycoprotein; MUC5; mucin 5, subtypes A and C, tracheobronchial/gastric; mucin 5AC, oligomeric mucus/gel-forming pseudogene; mucin 5AC, oligomeric mucus/gel-forming; mucin-5 subtype AC, tracheobronchial; mucin-5AC; TBM; tracheobronchial mucin
Molecular Weight
Mass (kDA):
585.57 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11p15.5 |
| Sequence: | 11; NC_000011.10 (1157953..1201138) |
Tissue Specificity
Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia. Overexpressed in a number of carcinomas. Also expressed in Barrett's esophagus epithelium and in the proximal duodenum.
Subcellular Localizations
Secreted.
Diseases
- Neoplasms
- Carcinoma
- Adenocarcinoma
- Malignant Neoplasms
- Mucinous Adenocarcinoma
- Inflammation
- Metaplasia
- Asthma
- Hyperplasia
- Stomach Neoplasms
- Lung Diseases
- Conjunctival Diseases
- Adenoma
Pathways
- Secretion
- Pathogenesis
- Glycosylation
- Mucus Secretion
- Cell Differentiation
- Localization
- Cell Proliferation
- Transport
- Immune Response
- Inflammatory Response
- Reverse Transcription
- Sensitization
- Cell Adhesion
PTMs
- Phosphorylation
- Glycosylation
- Cleavage
- Methylation
- Deglycosylation
- Reduction
- Oxidation
- Myristoylation
- Sulphation
- Dephosphorylation
Research Areas
- Extracellular Matrix
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MUC5AC
bosterbio.com/bosterbio-gene-info-cards/MUC5AC
References
PMID: 11535137 by Escande F., et al. Human mucin gene MUC5AC: organization of its 5'-region and central repetitive region.
PMID: 9506983 by Li D., et al. Cloning of the amino-terminal and 5'-flanking region of the human MUC5AC mucin gene and transcriptional up-regulation by bacterial exoproducts.
2 Publications of Boster Mucin-5AC Antibodies & ELISA Kits
- PubMed ID: 34160729, Huang J,Liu J,Chang G,Wang Y,Ma N,Roy AC,Shen X.Glutamine Supplementation Attenu...
- PubMed ID: 23392769, Zhou J, Perelman Jm, Kolosov Vp, Zhou X. Mol Cell Biochem. 2013 May;377(1-2):75-...
*More publications can be found for each product on its corresponding product page