|Ig Isotype||Mouse IgG2a/ IgG1|
|Product Name||Anti-PCK Antibody (Monoclonal, C-11+PCK-26+CY-90+KS-1A3+M20+A53-B/A2)|
|Storage & Handling||At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.|
|Description||Mouse IgG monoclonal antibody for PCK detection. Tested with WB, IHC-P, IHC-F in Human;rat. No cross reactivity with other proteins.|
|Cite This Product||Anti-PCK Antibody (Monoclonal, C-11+PCK-26+CY-90+KS-1A3+M20+A53-B/A2) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1081)|
|Immunogen||mixture of several monoclonal cytokeratin clones.|
Assay Dilutions Overview
Immunohistochemistry(Frozen Section), 0.1-0.5μg/ml, Human, rat, -
Western blot, 1-2μg/ml, Human, rat
Boster's Secondary Antibodies And IHC, WB Kits
The following reagents are used to generate the images below.Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P) and IHC(F).
Images And Assay Conditions
Anti-PCK antibody (monoclonal), MA1081, IHC(P)
IHC(P): Human Placenta Tissue
Protein Target Info (Source: Uniprot.org)
|Protein Name||Keratin, type II cytoskeletal 1|
|Tissue Specificity||The source of this protein is neonatal foreskin. The 67-kDa type II keratins are expressed in terminally differentiating epidermis.|
|Alternative Names||Keratin, type II cytoskeletal 1;67 kDa cytokeratin;Cytokeratin-1;CK-1;Hair alpha protein;Keratin-1;K1;Type-II keratin Kb1;KRT1;KRTA;|
|Subcellular Localization||Cell membrane . Located on plasma membrane of neuroblastoma NMB7 cells.|
|Molecular Weight||66039 MW|
*if product is indicated to react with multiple species, protein info is based on the human gene.
|Protein Function||May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein kinase C (RACK1/GNB2L1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK. .|
|Background||Monoclonal anti cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. Monoclonal Anti Pan Cytokeratin(mixture) is a broadly reactive reagent, which recognizes epitopes present in most human epithelial tissues.|
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