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- Table of Contents
KRT1 Antibodies
AND KRT1 ELISA kits, KRT1 Proteins
Many biological assays use antibodies to detect KRT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KRT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KRT1 antibodies...
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KRT1 Infographic by Boster Bio
All KRT1 Products
Product
Figures
Specificity
Applications
Price
Anti-PCK Antibody (Monoclonal, C-11+PCK-26+CY-90+KS-1A3+M20+A53-B/A2)
8 Citations 7 Q&As
Human, Rat
IHC, WB
$370
Cat # MA1081
100 μg/vial
Cat # MA1081
100 μg/vial
Anti-Cytokeratin 1/KRT1 Antibody Picoband®
5 Citations
Human
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # A01639
100 µg/vial
Cat # A01639
100 µg/vial
Anti-Cytokeratin 1/Krt1 Antibody Picoband®
2 Citations
Mouse
ELISA, IF, IHC, WB
$370
Cat # A01639-1
100 µg/vial
Cat # A01639-1
100 µg/vial
KRT1 Overview
Facts about Keratin, type II cytoskeletal 1.
Keratin, type II cytoskeletal 1 (KRT1)
May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | KRT1 |
| Uniprot: | P04264 |
| Entrez: | 3848 |
Family
| Belongs to: |
|---|
| intermediate filament family |
Alternative Names
CK1; CK-1; cytokeratin 1; Cytokeratin-1; cytokeratin-1,67 kDa cytokeratin; EHK; EHK1; epidermolytic hyperkeratosis 1; EPPK; Hair alpha protein; K1; keratin 1; keratin, type II cytoskeletal 1; Keratin-1; KRT1A; KRTA; NEPPK; Type-II keratin Kb1
Molecular Weight
Mass (kDA):
66.039 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q13.13 |
| Sequence: | 12; NC_000012.12 (52674736..52680407, complement) |
Tissue Specificity
The source of this protein is neonatal foreskin. The 67-kDa type II keratins are expressed in terminally differentiating epidermis.
Subcellular Localizations
Cell membrane. Located on plasma membrane of neuroblastoma NMB7 cells.
Diseases
- Bullous Congenital Ichthyosiform Erythroderma (disorder)
- Hyperkeratosis
- Palmoplantar Keratosis
- Ichthyoses
- Exfoliative Dermatitis
- Ichthyosiform Erythroderma, Congenital
- Bulla
- Keratoderma, Palmoplantar, Epidermolytic
- Carcinoma
- Skin Diseases, Genetic
- Dermatologic Disorders
Interacting Proteins
- GOLGA2
- KRT15
- KRT33B
- NUP62
- TRIM27
Pathways
- Keratinocyte Differentiation
- Keratinization
- Translation
- Wound Healing
- Cornification
- Dna Methylation
- Methylation
- Pathogenesis
- Cell Migration
- Response To Peptidoglycan
- Aging
- Fertilization
- Skin Development
PTMs
- Methylation
Research Areas
- Cell Biology
- Cellular Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KRT1
bosterbio.com/bosterbio-gene-info-cards/KRT1
References
PMID: 2580302 by Johnson L.D., et al. Structure of a gene for the human epidermal 67-kDa keratin.
PMID: 10903910 by Whittock N.V., et al. Genomic organization and amplification of the human epidermal type II keratin genes K1 and K5.
3 Publications of Boster KRT1 Antibodies & ELISA Kits
- PubMed ID: 26870216, A metanephric adenoma of the kidney associated with polycythemia: A case report
- PubMed ID: 24962416, Stanniocalcin-1 protects bovine intestinal epithelial cells from oxidative stres...
- PubMed ID: 23185403, Bai J, Liu H, Li D, Cui L, Wu X. Plos One. 2012;7(11):E49673. Doi: 10.1371/Journ...
*More publications can be found for each product on its corresponding product page