Anti-Prolactin Receptor/PRLR Antibody

Prolactin R antibody

Boster Bio Anti-Prolactin Receptor/PRLR Antibody catalog # PA2087. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. Cited in 1 publication(s).

Product Info Summary

SKU: PA2087
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IHC, WB

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Product Name

Anti-Prolactin Receptor/PRLR Antibody

View all Prolactin R Antibodies

SKU/Catalog Number

PA2087

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Prolactin Receptor/PRLR Antibody catalog # PA2087. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Prolactin Receptor/PRLR Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2087)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of mouse PRLR, identical to the related rat sequence, and different from the related human sequence by three amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA2087 is reactive to PRLR in Human, Mouse, Rat

Applications

PA2087 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

95 kDa

Calculated molecular weight

69.506kDa

Background of Prolactin R

PRLR (Prolactin Receptor), is a cytokine receptor. By somatic cell hybrid analysis and by in situ hybridization, Arden et al. (1989, 1990) demonstrated that the prolactin receptor gene resides in the same chromosomal region as the growth hormone receptor gene, which has been mapped to 5p13-p12. Cunningham et al. (1990) demonstrated that zinc greatly increases the affinity of GH for the extracellular binding domain of PRLR, although it is not required for binding of GH to the growth hormone receptor or for binding of prolactin to the prolactin receptor. By mutational analysis, they showed that a cluster of 3 residues (histidine-18, histidine-21, and glutamic acid-174) in GH and histidine-188 in PRLR (conserved in all PRL receptors but not GH receptors) are likely zinc-ion ligands.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Rat, Mouse, By Heat
Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat

Validation Images & Assay Conditions

Gene/Protein Information For PRLR (Source: Uniprot.org, NCBI)

Gene Name

PRLR

Full Name

Prolactin receptor

Weight

69.506kDa

Superfamily

type I cytokine receptor family

Alternative Names

delta 4-delta 7/11 truncated prolactin receptor; delta 4-SF1b truncated prolactin receptor; hPRL receptor; hPRLrI; PRLR; PRL-R; Prolactin R; prolactin receptor delta 7/11; prolactin receptor; ProlactinR; secreted prolactin binding protein PRLR HPRL, MFAB, RI-PRLR, hPRLrI prolactin receptor prolactin receptor|hPRL receptor|secreted prolactin binding protein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on PRLR, check out the PRLR Infographic

PRLR infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for PRLR: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

PA2087 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

miR-182 aids in receptive endometrium development in dairy goats by down-regulating PTN expression

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4 Customer Q&As for Anti-Prolactin Receptor/PRLR Antibody

Question

I was wanting to use your anti-Prolactin Receptor/PRLR antibody for IHC-P for human mammary carcinoma on frozen tissues, but I want to know if it has been validated for this particular application. Has this antibody been validated and is this antibody a good choice for human mammary carcinoma identification?

Verified Customer

Verified customer

Asked: 2020-02-19

Answer

You can see on the product datasheet, PA2087 anti-Prolactin Receptor/PRLR antibody has been tested for IHC-P, WB on human, mouse, rat tissues. We have an innovator award program that if you test this antibody and show it works in human mammary carcinoma in IHC-frozen, you can get your next antibody for free.

Boster Scientific Support

Answered: 2020-02-19

Question

Is a blocking peptide available for product anti-Prolactin Receptor/PRLR antibody (PA2087)?

Verified Customer

Verified customer

Asked: 2019-10-31

Answer

We do provide the blocking peptide for product anti-Prolactin Receptor/PRLR antibody (PA2087). If you would like to place an order for it please contact [email protected] and make a special request.

Boster Scientific Support

Answered: 2019-10-31

Question

Please see the WB image, lot number and protocol we used for mammary carcinoma using anti-Prolactin Receptor/PRLR antibody PA2087. Please let me know if you require anything else.

Verified Customer

Verified customer

Asked: 2018-06-18

Answer

Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2018-06-18

Question

Is there a BSA free version of anti-Prolactin Receptor/PRLR antibody PA2087 available?

J. Roberts

Verified customer

Asked: 2018-05-01

Answer

We appreciate your recent telephone inquiry. I can confirm that some lots of this anti-Prolactin Receptor/PRLR antibody PA2087 are BSA free. For now, these lots are available and we can make a BSA free formula for you free of charge. It will take 3 extra days to prepare. If you require this antibody BSA free again in future, please do not hesitate to contact me and I will be pleased to check which lots we have in stock that are BSA free.

Boster Scientific Support

Answered: 2018-05-01

Order DetailsPrice
PA2087

100μg

$370
PA2087-10ug

10μg sample (liquid)

$99
PA2087-Biotin

100 μg Biotin conjugated

$570
PA2087-Cy3

100 μg Cy3 conjugated

$570
PA2087-Dylight488

100 μg Dylight488 conjugated

$570
PA2087-Dylight550

100 μg Dylight550 conjugated

$570
PA2087-Dylight594

100 μg Dylight594 conjugated

$570
PA2087-FITC

100 μg FITC conjugated

$570
PA2087-HRP

100 μg HRP conjugated

$570
PA2087-APC

100 μg APC conjugated

$670
PA2087-PE

100 μg PE conjugated

$670
PA2087-carrier-free

Carrier Free

$370

More conjugates/formats

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PA2087
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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