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- Table of Contents
Prolactin receptor Antibodies
AND PRLR ELISA kits, Prolactin receptor Proteins
Many biological assays use antibodies to detect Prolactin receptor, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Prolactin receptor in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Prolactin receptor antibodies...
Designing a Western blot for Prolactin receptor? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PRLR Western Blot GuidePRLR Infographic by Boster Bio
All PRLR Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IHC, WB
$370
Cat # PA2087
100 μg/vial
Cat # PA2087
100 μg/vial
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M01196-2
100 μl
Cat # M01196-2
100 μl
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01196-5
100 μg
Cat # M01196-5
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01196-4
100 μg
Cat # M01196-4
100 μg
Human
$628
Cat # LS005618
20 µg, 100 µg
Cat # LS005618
20 µg, 100 µg
PRLR Overview
Facts about Prolactin receptor.
Prolactin receptor (PRLR)
This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival element for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase stimulation and activation of AKT.
Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.
Gene Information
| Human | |
|---|---|
| Gene Name: | PRLR |
| Uniprot: | P16471 |
| Entrez: | 5618 |
Family
| Belongs to: |
|---|
| type I cytokine receptor family |
Alternative Names
delta 4-delta 7/11 truncated prolactin receptor; delta 4-SF1b truncated prolactin receptor; hPRL receptor; hPRLrI; PRLR; PRL-R; Prolactin R; prolactin receptor delta 7/11; prolactin receptor; ProlactinR; secreted prolactin binding protein
Molecular Weight
Mass (kDA):
69.506 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5p13.2 |
| Sequence: | 5; NC_000005.10 (35048756..35230724, complement) |
Tissue Specificity
Expressed in breast, placenta, kidney, liver and pancreas.
Subcellular Localizations
Membrane; Single-pass type I membrane protein.; [Isoform 7]: Secreted.
Diseases
- Malignant Neoplasms
- Pituitary Diseases
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Neoplasms
- Carcinoma
- Janiceps
- Cell Transformation, Neoplastic
- Lymphoma
- Infertility
- Malignant Paraganglionic Neoplasm
- Mammary Neoplasms, Experimental
- Hyperprolactinemia
Interacting Proteins
- PRL
- YWHAZ
Pathways
- Lactation
- Secretion
- Cell Proliferation
- Localization
- Gland Development
- Pathogenesis
- Mammary Gland Development
- Ovulation
- Cell Growth
- Reverse Transcription
- Embryo Implantation
- Transport
- Cell Differentiation
PTMs
- Phosphorylation
- Glycosylation
- Cleavage
- Dephosphorylation
- Deglycosylation
Research Areas
- Apoptosis
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRLR
bosterbio.com/bosterbio-gene-info-cards/PRLR
References
PMID: 2558309 by Boutin J.-M., et al. Identification of a cDNA encoding a long form of prolactin receptor in human hepatoma and breast cancer cells.
PMID: 10585417 by Kline J.B., et al. Functional characterization of the intermediate isoform of the human prolactin receptor.
1 Publications of Boster Prolactin receptor Antibodies & ELISA Kits
- PubMed ID: 28678802, miR-182 aids in receptive endometrium development in dairy goats by down-regulat...
*More publications can be found for each product on its corresponding product page