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Product Info Summary
| SKU: | A11841 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Rat |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-PRTFDC1 Antibody
SKU/Catalog Number
A11841
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-PRTFDC1 Antibody (Catalog # A11841). Tested in ELISA, WB applications. This antibody reacts with Human, Rat.
Storage & Handling
PRTFDC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-PRTFDC1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11841)
Host
Rabbit
Contents
PRTFDC1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
PRTFDC1 antibody was raised against a 14 amino acid synthetic peptide from near the center of human PRTFDC1. The immunogen is located within amino acids 90 - 140 of PRTFDC1.
Reactive Species
A11841 is reactive to PRTFDC1 in Human, Rat
Observed Molecular Weight
68 kDa
Calculated molecular weight
25.7 kDa
Background of PRTFDC1
Phosphoribosyl transferase domain containing 1 (PRTFDC1) is highly homologous to the hypoxanthine phosphoribosyltransferase (HPRT1) and may have arisen from a gene duplication event of a common ancestor gene. Recently, it was shown that CpG islands in the PRTFDC1 promoter could be hypermethylated in ovarian cancers and oral squamous-cell carcinomas (OSCC), leading to gene silencing. Restoration of PRTFDC1 expression in OSCC inhibited cell growth in colony-formation assays, while knockdown of PRTFDC1 expression in OSCC that expressed the gene promoted cell growth. These results suggest that PRTFDC1 can act as a tumor-suppressor gene. At least three isoforms of PRTFDC1 are known to exist.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A11841 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
PRTFDC1 antibody can be used for detection of PRTFDC1 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of PRTFDC1 in human brain tissue lysate with PRTFDC1 antibody at 1 μg/mL in the (A) absence and (B) presence of blocking peptide.
Specific Publications For Anti-PRTFDC1 Antibody (A11841)
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