Anti-RPTOR Antibody

RPTOR antibody

Boster Bio Anti-RPTOR Antibody (Catalog # M01463-1). Tested in IHC-P, WB application(s). This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: M01463-1
Size: 80 µl
Reactive Species: Human, Mouse, Rat
Host: Mouse
Application: IHC-P, WB

Product Name

Anti-RPTOR Antibody

View all RPTOR Antibodies

SKU/Catalog Number

M01463-1

Size

80 µl

Description

Boster Bio Anti-RPTOR Antibody (Catalog # M01463-1). Tested in IHC-P, WB application(s). This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Cite This Product

Anti-RPTOR Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01463-1)

Host

Mouse

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Clonality

Monoclonal

Clone Number

1411CT316.2.151.34

Isotype

IgG1,k

Immunogen

This RPTOR antibody is generated from a mouse immunized with recombinant protein.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M01463-1 is reactive to RPTOR in Human, Mouse, Rat

Applications

M01463-1 is guaranteed for IHC-P, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

149.038kDa

Background of RPTOR

Involved in the control of the mammalian target of rapamycin complex 1 (mTORC1) activity which regulates cell growth and survival, and autophagy in response to nutrient and hormonal signals; functions as a scaffold for recruiting mTORC1 substrates. mTORC1 is activated in response to growth factors or amino acids. Growth factor-stimulated mTORC1 activation involves a AKT1- mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E). mTORC1 phosphorylates and activates S6K1 at 'Thr-389', which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation. Involved in ciliogenesis.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.

Submit A Review

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:1000
IHC-P: 1:25

Validation Images & Assay Conditions

Gene/Protein Information For RPTOR (Source: Uniprot.org, NCBI)

Gene Name

RPTOR

Full Name

Regulatory-associated protein of mTOR

Weight

149.038kDa

Superfamily

WD repeat RAPTOR family

Alternative Names

KIAA1303; KIAA1303p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats; KOG1; Mip1; p150 target of rapamycin (TOR)-scaffold protein; Raptor; regulatory associated protein of MTOR, complex 1; regulatory-associated protein of mTOR; RPTOR RPTOR KOG1, Mip1 regulatory associated protein of MTOR complex 1 regulatory-associated protein of mTOR|p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats|raptor

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on RPTOR, check out the RPTOR Infographic

RPTOR infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for RPTOR: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

No publications found for M01463-1

*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.

Have you used Anti-RPTOR Antibody?

Submit a review and receive an Amazon gift card.

  • $25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
  • $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit A Review

Be the first to review Anti-RPTOR Antibody

*The first user to submit a review for a product is eligible for Boster's Innovating Scientists Reward, which gives product credits. This is in addition to the gift card reward.

Have a question?

Find answers in Q&As, reviews.

Can't find your answer?

Submit your question

0 Customer Q&As for Anti-RPTOR Antibody

Order DetailsPrice
M01463-1-80ul

80 µl

$298
M01463-1-400ul

400 µl

$460

Free Secondary Antibody

Choose an option to show lead time.
Get A Quote
Eddy test
In stock
Order Product
M01463-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$298.00

Troubleshooting

troubleshooting-box-image

Download troubleshooting handbooks for IHC, Western blot and ELISA for FREE.

Download Free PDFs Now

Boster Guarantee

Guaranteed product quality

Guaranteed product quality

We promise all of our products perform as described in datasheets.