Product Info Summary
SKU: | A03376 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IF, IHC, ICC, WB |
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Product info
Product Name
Anti-SPTA1 Antibody
View all Spectrin alpha 1 Antibodies
SKU/Catalog Number
A03376
Size
100ul
Form
Liquid
Description
Boster Bio Anti-SPTA1 Antibody catalog # A03376. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-SPTA1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03376)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human SFTPD protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A03376 is reactive to SPTA1 in Human, Mouse, Rat
Applications
A03376 is guaranteed for IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
280.014kDa
Background of Spectrin alpha 1
Transfers the acyl group from the sn-1 position of phosphatidylcholine to all-trans retinol, producing all-trans retinyl esters. Retinyl esters are storage forms of vitamin A. LRAT plays a critical role in vision. It provides the all-trans retinyl ester substrates for the isomerohydrolase which processes the esters into 11-cis-retinol in the retinal pigment epithelium; due to a membrane-associated alcohol dehydrogenase, 11 cis-retinol is oxidized and converted into 11-cis-retinaldehyde which is the chromophore for rhodopsin and the cone photopigments.
Ruiz A., J. Biol. Chem. 274:3834-3841(1999).
Mondal M.S., Biochemistry 39:5215-5220(2000).
Thompson D.A., Nat. Genet. 28:123-124(2001).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-SPTA1 Antibody A03376
Western blot analysis of extracts of various cell linesProtein Target Info & Infographic
Gene/Protein Information For SPTA1 (Source: Uniprot.org, NCBI)
Gene Name
SPTA1
Full Name
Spectrin alpha chain, erythrocytic 1
Weight
280.014kDa
Superfamily
spectrin family
Alternative Names
alpha-I spectrin; EL2; erythrocyte; HS3; spectrin, alpha, erythrocytic 1 (elliptocytosis 2) SPTA1 EL2, HPP, HS3, SPH3, SPTA spectrin alpha, erythrocytic 1 spectrin alpha chain, erythrocytic 1|alpha-I spectrin|elliptocytosis 2|erythroid alpha-spectrin|spectrin alpha chain, erythrocyte
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SPTA1, check out the SPTA1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SPTA1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SPTA1 Antibody (A03376)
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No publications found for A03376
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