SPTA1 Antibodies

AND SPTA1 ELISA kits, SPTA1 Proteins

Many biological assays use antibodies to detect SPTA1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SPTA1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SPTA1 antibodies...

We validate the specificity of these antibodies to SPTA1 by testing them on tissues known to express SPTA1 positively and negatively. Browse below to find the SPTA1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SPTA1 Infographic by Boster Bio

All SPTA1 Products

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Anti-SPTA1 Rabbit Monoclonal Antibody

6 Q&As

Western blot analysis of SPTA1 expression in K562 cell lysate

Human

IHC, WB

$370
Cat # M03376
100 μl

Anti-SPTA1 Antibody

Western blot analysis of extracts of various cell lines, using alpha 1 Spectrin antibody at 1:3000 dilution

Immunohistochemistry of paraffin-embedded human tonsil using alpha 1 Spectrin antibody at dilution of 1:100

Immunohistochemistry of paraffin-embedded rat spleen using alpha 1 Spectrin antibody at dilution of 1:100

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A03376
100ul

Anti-alpha 1 Spectrin Rabbit Monoclonal Antibody

1 Citations

Western blot analysis of alpha 1 Spectrin expression in K562 cell lysate

Human, Mouse, Rat

Flow Cytometry, IF, ICC, WB

$370
Cat # M03376-1
100 μl/vial

alpha 1 Spectrin (SPTA1) (NM_003126) Human Over-expression Lysate

Human

$960
Cat # LS006708
20 µg, 100 µg

SPTA1 Overview

Facts about Spectrin alpha chain, erythrocytic 1.

Spectrin alpha chain, erythrocytic 1 (SPTA1)

Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.

1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. .

Gene Information

Human
Gene Name:	SPTA1
Uniprot:	P02549
Entrez:	6708

Family

Belongs to:

spectrin family

Alternative Names

alpha-I spectrin; EL2; erythrocyte; HS3; spectrin, alpha, erythrocytic 1 (elliptocytosis 2)

Molecular Weight

Mass (kDA):
280.014 kDA

Genomic Context


Human

Location:	1q23.1
Sequence:	1; NC_000001.11 (158610498..158686715, complement)

Subcellular Localizations

Cytoplasm, cytoskeleton. Cytoplasm, cell cortex.

Diseases

Hereditary Spherocytosis
Elliptocytosis, Hereditary
Anemia
Anemia, Hemolytic, Congenital
Hereditary Diseases
Hydrops Fetalis
Dehydration
Hemolysis (disorder)
Edema
Hereditary Stomatocytosis
Diabetes Mellitus
Hereditary Pyropoikilocytosis

Anemia, Hemolytic
Stomatocytic Anemia
Pseudohyperkalaemia
Malignant Neoplasm Of Breast
Carcinoma
Disorders Of Porphyrin Metabolism
Porphyrias, Hepatic

Interacting Proteins

ABI1
SPTB
SPTBN1

Pathways

Transport
Regulation Of Cell Cycle
Reverse Transcription
Cell Cycle
Fertilization
Prophase
Oocyte Maturation
Pathogenesis

Insemination
Embryo Development

PTMs

Phosphoprotein

Research Areas

Cell Biology
Cellular Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SPTA1

References

PMID: 1689726 by Sahr K.E., et al. The complete cDNA and polypeptide sequences of human erythroid alpha- spectrin.

PMID: 2794061 by Sahr K.E., et al. Sequence and exon-intron organization of the DNA encoding the alpha I domain of human spectrin. Application to the study of mutations causing hereditary elliptocytosis.

1 Publications of Boster SPTA1 Antibodies & ELISA Kits

PubMed ID: 10.1016/j.aanat.2020.151647, Immunohistochemical evidence of striated muscle cells within midfacial superfici...

*More publications can be found for each product on its corresponding product page