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Product Info Summary
|Reactive Species:||Human, Mouse|
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Anti-TCF7 Antibody Picoband™
Boster Bio Anti-TCF7 Antibody Picoband™ catalog # A01315-2. Tested in WB applications. This antibody reacts with Human, Mouse.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-TCF7 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01315-2)
Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
A synthetic peptide corresponding to a sequence of human TCF7 (KQELQPFDRNLKTQAESKAEKEAKKPTIKKPL).
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
No cross reactivity with other proteins.
A01315-2 is reactive to TCF7 in Human, Mouse
A01315-2 is guaranteed for WB Boster Guarantee
Background of TCF7/TCF1
Transcription factor 7 is a protein that in humans is encoded by the TCF7 gene. It is mapped to 5q31.1. This gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. This gene is expressed predominantly in T-cells and plays a critical role in natural killer cell and innate lymphoid cell development. The encoded protein forms a complex with beta-catenin and activates transcription through a Wnt/beta-catenin signaling pathway. Mice with a knockout of this gene are viable and fertile, but display a block in T-lymphocyte differentiation. Alternative splicing results in multiple transcript variants. Naturally-occurring isoforms lacking the N-terminal beta-catenin interaction domain may act as dominant negative regulators of Wnt signaling.
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.
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Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.
Western blot, 0.1-0.5μg/ml
Validation Images & Assay Conditions
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Boster Kit Box
Gene/Protein Information For TCF7 (Source: Uniprot.Org, NCBI)
Transcription factor 7
FLJ36364; MGC47735; T-cell factor 1; T-cell specific; TCF1; TCF7; TCF-7; transcription factor 7 (T-cell specific, HMG-box) TCF7 TCF-1 transcription factor 7 transcription factor 7|T-cell-factor-7|T-cell-specific transcription factor 1|transcription factor 7 (T-cell specific, HMG-box)*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".
For more info on TCF7, check out the TCF7 Infographic
We have 30,000+ of these available, one for each gene! check them out.
In this infographic you will see the following information for TCF7: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]
A01315-2 has been cited in 1 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
LncRNA4930473A02Rik promotes cardiac hypertrophy by regulating TCF7 via sponging miR-135a in mice
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