Anti-TLR2 Antibody Picoband®

Product Name

Anti-TLR2 Antibody Picoband®

View all TLR2 Antibodies

SKU/Catalog Number

A00131

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-TLR2 Antibody Picoband® catalog # A00131. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

TLR2 signals via MYD88 and TRAF6 leading to NF-κB activation, cytokine secretion, and inflammatory responses (well-established). Assay context: primary antibody reactive with human, validated for WB on the product page. TLR2 pathway activation is often evaluated by WB of downstream nodes (e.g., phospho-signaling or adaptor abundance; study-dependent), aligning with methodological considerations in Western blotting or higher-throughput in-cell western blot; innate immune interpretation can be complemented by myeloid activation markers such as TREM2 (putative).

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-TLR2 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00131)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human TLR2 recombinant protein (Position: H610-S784). Human TLR2 shares 87.4% amino acid (aa) sequence identity with mouse TLR2.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A00131 is reactive to TLR2 in Human

Observed Molecular Weight

105 kDa

Calculated molecular weight

89.8 kDa

Background of TLR2

Toll-like receptor 2, also known as TLR-2, is a protein that in humans is encoded by the TLR2 gene. It has also been designated as CD282 (cluster of differentiation 282). TLR-2 plays a role in the immune system. And TLR-2 is a membrane protein, a receptor, which is expressed on the surface of certain cells and recognizes foreign substances and passes on appropriate signals to the cells of the immune system. TLR2 expresses as 4- and 4.4-kb mRNAs in heart, brain, and muscle.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A00131 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human

Positive Control

WB: human THP-1 (-LPS) whole cell, human THP-1 (+LPS) whole cell, human Hacat whole cell, human PC-3 whole cell, human Caco-2 whole cell, human HepG2 whole cell

Validation Images & Assay Conditions

See full target information TLR2

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