Product Info Summary
SKU: | M00410-2 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse |
Host: | Mouse |
Application: | ICC, WB |
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Product info
Product Name
Anti-TNFRSF10B / DR5 monoclonal Antibody
View all TRAILR2/TNFRSF10B Antibodies
SKU/Catalog Number
M00410-2
Size
100ul
Form
Liquid
Description
Boster Bio Anti-TNFRSF10B / DR5 monoclonal Antibody catalog # M00410-2. Tested in WB,ICC applications. This antibody reacts with Human,Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-TNFRSF10B / DR5 monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00410-2)
Host
Mouse
Contents
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Monoclonal
Clone Number
10F8D7
Isotype
IgG
Immunogen
Purified recombinant fragment of MLL (aa3751-3968) expressed in E. Coli.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M00410-2 is reactive to TNFRSF10B in Human, Mouse
Applications
M00410-2 is guaranteed for ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
47.878kDa
Background of TRAILR2/TNFRSF10B
Paired box protein Pax-6 also known as aniridia type II protein (AN2) or oculorhombin is a transcription factor with key functions in the development of the eye, nose, central nervous system and pancreas. Pax6 further seems to be required for the differentiation of pancreatic islet alpha cells. PAX6 has been shown to bind to a promoter element in the glucagon, insulin and somatostatin promoters and regulates the specification of the ventral neuron subtypes by establishing the correct progenitor domains. Isoform 5a appears to function as a molecular switch that specifies target genes. Anti-PAX6 antibody is ideal for researchers interested in developmental biology, stem cell research, cell growth and cancer research.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-2000
ICC: 1:50-200
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For TNFRSF10B (Source: Uniprot.org, NCBI)
Gene Name
TNFRSF10B
Full Name
Tumor necrosis factor receptor superfamily member 10B
Weight
47.878kDa
Alternative Names
CD262 antigen; CD262; death domain containing receptor for TRAIL/Apo-2L; Death receptor 5; DR5; DR5TRICK2B; Fas-like protein; KILLER/DR5; KILLERapoptosis inducing protein TRICK2A/2B; TNF-related apoptosis-inducing ligand receptor 2; TNFRSF10B; TRAIL R2; TRAIL receptor 2; TRAILR2; TRAIL-R2apoptosis inducing receptor TRAIL-R2; TRAILR2cytotoxic TRAIL receptor-2; TRICK2; TRICK2A; TRICKB; tumor necrosis factor receptor superfamily member 10B; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor-like protein ZTNFR9; ZTNFR9 TNFRSF10B CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9 TNF receptor superfamily member 10b tumor necrosis factor receptor superfamily member 10B|Fas-like protein|TNF-related apoptosis-inducing ligand receptor 2|apoptosis inducing protein TRICK2A/2B|apoptosis inducing receptor TRAIL-R2|cytotoxic TRAIL receptor-2|death domain containing receptor for TRAIL/Apo-2L|death receptor 5|p53-regulated DNA damage-inducible cell death receptor(killer)|tumor necrosis factor receptor superfamily, member 10b|tumor necrosis factor receptor-like protein ZTNFR9
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TNFRSF10B, check out the TNFRSF10B Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TNFRSF10B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TNFRSF10B / DR5 monoclonal Antibody (M00410-2)
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No publications found for M00410-2
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