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Actin-related protein 3 Antibodies
AND ACTR3 ELISA kits, Actin-related protein 3 Proteins
Many biological assays use antibodies to detect Actin-related protein 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Actin-related protein 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Actin-related protein 3 antibodies...
Designing a Western blot for Actin-related protein 3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ACTR3 Western Blot GuideACTR3 Infographic by Boster Bio
All ACTR3 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M03423-1
100 μl/vial
Cat # M03423-1
100 μl/vial
Anti-Arp3/ACTR3 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A03423-2
100 μg/vial
Cat # A03423-2
100 μg/vial
ACTR3 Overview
Facts about Actin-related protein 3.
Actin-related protein 3 (ACTR3)
ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9000076). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9000076).
Seems to contact the pointed end of their daughter actin filament (PubMed:9000076). Besides its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:17220302, PubMed:29925947).
Gene Information
| Human | |
|---|---|
| Gene Name: | ACTR3 |
| Uniprot: | P61158 |
| Entrez: | 10096 |
Family
| Belongs to: |
|---|
| actin family |
Alternative Names
actin-related protein 3; ARP3 (actin-related protein 3, yeast) homolog; ARP3 actin-related protein 3 homolog (yeast); ARP3Actin-like protein 3
Molecular Weight
Mass (kDA):
47.371 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q14.1 |
| Sequence: | 2; NC_000002.12 (113889934..113962596) |
Subcellular Localizations
Cytoplasm, cytoskeleton. Cell projection. Nucleus. In pre-apoptotic cells, colocalizes with MEFV in large specks (pyroptosomes) (PubMed:19109554).
Diseases
- Wiskott-aldrich Syndrome
- Tissue Adhesions
- Protrusion
- Shigella Infections
- Spinocerebellar Ataxia, Autosomal Recessive 1
- Vaccinia
- Malignant Neoplasms
- Cell Invasion
- Neoplasm Metastasis
- Immunologic Deficiency Syndromes
- Dysplasia
- Nervousness
Interacting Proteins
- JUND
Pathways
- Actin Nucleation
- Localization
- Cell Motility
- Endocytosis
- Locomotion
- Cell Migration
- Transport
- Phagocytosis
- Clathrin-mediated Endocytosis
- Receptor-mediated Endocytosis
- Chemotaxis
- Arp2/3 Complex-mediated Actin Nucleation
- Hemostasis
PTMs
- Phosphorylation
- Dephosphorylation
- Prenylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACTR3
bosterbio.com/bosterbio-gene-info-cards/ACTR3
References
PMID: 9230079 by Welch M.D., et al. The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly.
PMID: 9000076 by Welch M.D., et al. Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes.