Actin-related protein 3 Antibodies

AND ACTR3 ELISA kits, Actin-related protein 3 Proteins

Many biological assays use antibodies to detect Actin-related protein 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Actin-related protein 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Actin-related protein 3 antibodies...

We validate the specificity of these antibodies to Actin-related protein 3 by testing them on tissues known to express ACTR3 positively and negatively. Browse below to find the ACTR3 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ACTR3 Infographic by Boster Bio

All ACTR3 Products

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Western blot (WB) analysis of ACTR3 polyclonal antibody at 1:500 dilution
Lane1:Hela cell lysate
Lane2:NIH-3T3 cell lysate
Lane3:PC12 cell lysate

Immunohistochemistry (IHC) analyzes of ACTR3 pAb in paraffin-embedded human tonsil carcinoma tissue at 1:50,showing cytoplasmic and perinuclear staining

Immunohistochemistry (IHC) analyzes of ACTR3 pAb in paraffin-embedded human stomach carcinoma tissue at 1:50,showing cytoplasmic and perinuclear staining

Human, Mouse, Rat

IHC, WB

$405
Cat # A03423
100ul

Anti-Arp3 ACTR3 Antibody

Western blot analysis of Arp3 on different lysates using anti-Arp3 antibody at 1/500 dilution

ICC staining Arp3 in HUVEC cells (green)

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$405
Cat # A03423-1
100ul

Anti-Arp3/ACTR3 Antibody Picoband®

1 Citations

Western blot analysis of Arp3/ACTR3 using anti-Arp3/ACTR3 antibody (A03423-2)

Flow Cytometry analysis of A431 cells using anti-Arp3/ACTR3 antibody (A03423-2)

Flow Cytometry analysis of ANA-1 cells using anti-Arp3/ACTR3 antibody (A03423-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A03423-2
100 μg/vial

Human ACTR3 Recombinant Protein

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

SDS-PAGE, Denatured

$250
Cat # PROTP61158
Starting from 20ug

Anti-Arp3 (ACTR3) Mouse Monoclonal Antibody [Clone ID: OTI5G4]

Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-ACTR3 mouse monoclonal antibody

Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-ACTR3 mouse monoclonal antibody

Immunohistochemical staining of paraffin-embedded Human spleen tissue within the normal limits using anti-ACTR3 mouse monoclonal antibody

Human, Mouse, Rat

IHC, WB

$523
Cat # M03423
100 µl

Anti-Arp3 Rabbit Monoclonal Antibody

Western blot analysis of Arp3 expression in Jurkat cell lysate

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M03423-1
100 μl/vial

Arp3 (ACTR3) (NM_005721) Human Over-expression Lysate

Human

$628
Cat # LS010096
20 µg, 100 µg

ACTR3 Overview

Facts about Actin-related protein 3.

ACTR3 3D structure. Source: alphafold

Actin-related protein 3 (ACTR3)

ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9000076). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9000076).

Seems to contact the pointed end of their daughter actin filament (PubMed:9000076). Besides its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:17220302, PubMed:29925947).

Gene Information

Human
Gene Name:	ACTR3
Uniprot:	P61158
Entrez:	10096

Family

Belongs to:

actin family

Alternative Names

actin-related protein 3; ARP3 (actin-related protein 3, yeast) homolog; ARP3 actin-related protein 3 homolog (yeast); ARP3Actin-like protein 3

Molecular Weight

Mass (kDA):
47.371 kDA

Genomic Context


Human

Location:	2q14.1
Sequence:	2; NC_000002.12 (113889934..113962596)

Subcellular Localizations

Cytoplasm, cytoskeleton. Cell projection. Nucleus. In pre-apoptotic cells, colocalizes with MEFV in large specks (pyroptosomes) (PubMed:19109554).

Diseases

Wiskott-aldrich Syndrome
Tissue Adhesions
Protrusion
Shigella Infections
Spinocerebellar Ataxia, Autosomal Recessive 1
Vaccinia
Malignant Neoplasms
Cell Invasion
Neoplasm Metastasis
Immunologic Deficiency Syndromes
Dysplasia
Nervousness

Yersinia Infections
Neoplasms
Disease Caused By Shigella Flexneri
Adenocarcinoma
Tumor Progression
Bulla
Infective Disorder

Interacting Proteins

JUND

Pathways

Actin Nucleation
Localization
Cell Motility
Endocytosis
Locomotion
Cell Migration
Transport
Phagocytosis
Clathrin-mediated Endocytosis
Receptor-mediated Endocytosis
Chemotaxis
Arp2/3 Complex-mediated Actin Nucleation
Hemostasis

Actin Filament Network Formation
Tissue Remodeling
Cell Growth
Rna Interference
Secretion
Cell Adhesion
Platelet Activation

PTMs

Phosphorylation
Dephosphorylation
Prenylation

Cleavage
Methylation
Ribosylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACTR3

References

PMID: 9230079 by Welch M.D., et al. The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly.

PMID: 9000076 by Welch M.D., et al. Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes.