Disintegrin and metalloproteinase domain-containing protein 15 (ADAM15)

Plays a role in the wound healing process. Mediates equally heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation.

Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells. Suppresses cell motility towards or on fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation.