Adenylate cyclase type 6 Antibodies

Adenylate cyclase type 6 (ADCY6)

Functions in signaling cascades downstream of the vasopressin receptor in the kidney and has a role in renal water reabsorption. Functions in signaling cascades downstream of PTH1R and plays a role in regulating renal phosphate excretion.

Functions in signaling cascades downstream of the VIP and SCT receptors in pancreas and contributes to the regulation of pancreatic amylase and fluid secretion (By similarity). Signaling mediates cAMP-dependent activation of protein kinase PKA.

Gene Information

Human
Gene Name:	ADCY6
Uniprot:	O43306
Entrez:	112

Family

Belongs to:
adenylyl cyclase class-4/guanylyl cyclase family

Alternative Names

AC6; adenylate cyclase 6; adenylate cyclase type 6; Adenylate cyclase type VI; Adenylyl cyclase 6; ATP pyrophosphate-lyase 6; Ca(2+)-inhibitable adenylyl cyclase; DKFZp779F075; EC 4.6.1.1; KIAA0422

Molecular Weight

Mass (kDA):
130.615 kDA

Genomic Context

Human
Location:	12q13.12
Sequence:	12; NC_000012.12 (48766194..48789089, complement)

Tissue Specificity

Detected in peripheral blood mononuclear leukocytes (at protein level) (PubMed:17916776). Detected in thyroid (PubMed:10978539).

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Cell projection, cilium. Cell projection, stereocilium.

Diseases

• Laryngeal Squamous Cell Carcinoma
• Non-neoplastic Disorder
• Malignant Neoplasm Of Larynx
• Anemia, Sickle Cell
• Carcinoma
• Cardiovascular Diseases
• Malignant Neoplasms
• Malignant Neck Neoplasm
• Neoplasms
• Nervousness
• Asthma
• Dysequilibrium Syndrome

• Malignant Head And Neck Neoplasm
• Pathologic Vasoconstriction
• Malignant Squamous Cell Neoplasm
• Laryngeal Neoplasm
• Tissue Adhesions
• Major Depressive Disorder
• Hypertensive Disease

Pathways

• Cell Adhesion
• Vasodilation
• Reverse Transcription
• Circadian Rhythm
• Cell Cycle
• Proteolysis
• Dna Repair
• Cell Growth
• Regulation Of Gene Expression

• Regulation Of Cell Growth
• Oocyte Maturation
• Meiosis

PTMs

• Glycoprotein

• Phosphoprotein

Research Areas

• Lipid and Metabolism
• Vision

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ADCY6

Boster Bio: Best Uses Of The ADCY6 Marker

This article will provide information about the ADCY6 antibody, Anti-ADCY5/6 Antibody, as well as Steven Boster's past. The ADCY6 marker has many benefits. In addition, Boster Bio will be discussing Steven Boster’s background and career path. The information here is relevant for all scientists, worldwide.

Anti-ADCY5/6

The most frequently used marker for cancer research is the ADCY5/6. The ADCY5/6 Protein is found in tissues as well as cells of humans, mice, and eukaryotes. Scientists can submit their results and receive credit for their work by using this marker. It is also useful for scientists around the globe. Continue reading to learn about the ADCY5/6 gene, and its many uses.

AC5 protein can be found in almost all organs. The protein is at its highest in neonates and then decreases to the basal level in adults. It is elevated in the heart due to pressure-overload leftventricular hypertrophy. The AC5 antibody is very similar to the genes of fetal ancestry. For example, neonates are more likely to express the atrial nutriuretic peptide peptide gene than adults.

The AC5 MAb was tested for specificity against the AC5 isoform in mice. While the AC5 protein level was identical in WT and AC6TG mice, there was no significant cross-reactivity. AC5 MAb detects AC protein levels in mouse hearts. It has demonstrated high specificity. It is safe to use in research because it does not cross react with the AC5 isoform.

Anti-ADCY6 Signer

The Boster Bio Anti–ADCY6 Marker has been extensively tested in ELISA, immunofluorescence and in-vitro Hybridization. The antibody reacts with Humans, Rats, and Mice. The boster bio anti-ADCY6 antibody is available in several formats. Below are some examples for this marker. Each format comes with its own advantages and drawbacks.

History of Steven Boster

The past week has been filled with events and people associated with the late Steve Boster. After a long battle against COVID-19, he passed away in Madison WI on Sunday, June 26, 2022. Steve Boster is survived and buried by his children, Donald Sr. David Boster, Nina Mae Hall. He is survived by his two sisters, Kimberly Blanton & Tammy Boster as well his niece and nephew.

Steve loved his family, regardless of his love for southern gospel music or sports. He was always the first to call for assistance when his car started to break down at 2 AM. He would arrive at the rescue, even in below-freezing conditions. His assistance was available for any medical emergency, or simply to have a laugh. Below are the links to search Steven Boster's past.