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Adenylate cyclase type 6 Antibodies
AND ADCY6 ELISA kits, Adenylate cyclase type 6 Proteins
Many biological assays use antibodies to detect Adenylate cyclase type 6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Adenylate cyclase type 6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Adenylate cyclase type 6 antibodies...
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ADCY6 Infographic by Boster Bio
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ADCY6 Overview
Facts about Adenylate cyclase type 6.
Adenylate cyclase type 6 (ADCY6)
Functions in signaling cascades downstream of the vasopressin receptor in the kidney and has a role in renal water reabsorption. Functions in signaling cascades downstream of PTH1R and plays a role in regulating renal phosphate excretion.
Functions in signaling cascades downstream of the VIP and SCT receptors in pancreas and contributes to the regulation of pancreatic amylase and fluid secretion (By similarity). Signaling mediates cAMP-dependent activation of protein kinase PKA.
Gene Information
| Human | |
|---|---|
| Gene Name: | ADCY6 |
| Uniprot: | O43306 |
| Entrez: | 112 |
Family
| Belongs to: |
|---|
| adenylyl cyclase class-4/guanylyl cyclase family |
Alternative Names
AC6; adenylate cyclase 6; adenylate cyclase type 6; Adenylate cyclase type VI; Adenylyl cyclase 6; ATP pyrophosphate-lyase 6; Ca(2+)-inhibitable adenylyl cyclase; DKFZp779F075; EC 4.6.1.1; KIAA0422
Molecular Weight
Mass (kDA):
130.615 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q13.12 |
| Sequence: | 12; NC_000012.12 (48766194..48789089, complement) |
Tissue Specificity
Detected in peripheral blood mononuclear leukocytes (at protein level) (PubMed:17916776). Detected in thyroid (PubMed:10978539).
Subcellular Localizations
Cell membrane; Multi-pass membrane protein. Cell projection, cilium. Cell projection, stereocilium.
Diseases
- Laryngeal Squamous Cell Carcinoma
- Non-neoplastic Disorder
- Malignant Neoplasm Of Larynx
- Anemia, Sickle Cell
- Carcinoma
- Cardiovascular Diseases
- Malignant Neoplasms
- Malignant Neck Neoplasm
- Neoplasms
- Nervousness
- Asthma
- Dysequilibrium Syndrome
Pathways
- Cell Adhesion
- Vasodilation
- Reverse Transcription
- Circadian Rhythm
- Cell Cycle
- Proteolysis
- Dna Repair
- Cell Growth
- Regulation Of Gene Expression
PTMs
- Glycoprotein
Research Areas
- Lipid and Metabolism
- Vision
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ADCY6
bosterbio.com/bosterbio-gene-info-cards/ADCY6
References
PMID: 10978539 by Wicker R., et al. Cloning and expression of human adenylyl cyclase type VI in normal thyroid tissues.
PMID: 8476432 by Hellevuo K., et al. A novel adenylyl cyclase sequence cloned from the human erythroleukemia cell line.