AP1S3 Antibodies

AND AP1S3 ELISA kits, AP1S3 Proteins

Many biological assays use antibodies to detect AP1S3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AP1S3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AP1S3 antibodies...

We validate the specificity of these antibodies to AP1S3 by testing them on tissues known to express AP1S3 positively and negatively. Browse below to find the AP1S3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AP1S3 Infographic by Boster Bio

All AP1S3 Products

Product

Figures

Specificity

Applications

Price

AP1S3 (NM_001039569) Human Over-expression Lysate

Human

$628
Cat # LS130340
100 µg

AP1S3 Overview

Facts about AP-1 complex subunit sigma-3.

AP1S3 3D structure. Source: alphafold

AP-1 complex subunit sigma-3 (AP1S3)

Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.

Involved in TLR3 trafficking (PubMed:24791904). .

Gene Information

Human
Gene Name:	AP1S3
Uniprot:	Q96PC3
Entrez:	130340

Family

Belongs to:

adaptor complexes small subunit family

Alternative Names

AP-1 complex subunit sigma-3

Molecular Weight

Mass (kDA):
18.28 kDA

Genomic Context


Human

Location:	2q36.1
Sequence:	2; NC_000002.12 (223755326..223837582, complement)

Tissue Specificity

Widely expressed.

Subcellular Localizations

Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, clathrin-coated pit. Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.

Diseases

Psoriasis 15, pustular (PSORS15)

Interacting Proteins

AAGAB

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AP1S3

References

PMID: 11598180 by Boehm M., et al. Adaptins: the final recount.

PMID: 24791904 by Setta-Kaffetzi N., et al. AP1S3 mutations are associated with pustular psoriasis and impaired Toll-like receptor 3 trafficking.