This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about AP-4 complex subunit sigma-1.
They control the vesicular transport of proteins in different trafficking pathways (PubMed:10066790, PubMed:10436028). AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.
Human | |
---|---|
Gene Name: | AP4S1 |
Uniprot: | Q9Y587 |
Entrez: | 11154 |
Belongs to: |
---|
adaptor complexes small subunit family |
adapter-related protein complex 4 subunit sigma-1; adaptor-related protein complex 4, sigma 1 subunit; AP-4 complex subunit sigma-1; AP47B; CLA20; CLAPS4; CPSQ6; sigma 4; sigma-4-adaptin; sigma4-adaptin
Mass (kDA):
17.005 kDA
Human | |
---|---|
Location: | 14q12 |
Sequence: | 14; NC_000014.9 (31025106..31096450) |
Widely expressed.
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein.
PMID: 10436028 by Hirst J., et al. Characterization of a fourth adaptor-related protein complex.
PMID: 10066790 by Dell'Angelica E.C., et al. AP-4, a novel protein complex related to clathrin adaptors.