Apolipoprotein B receptor Antibodies

AND APOBR ELISA kits, Apolipoprotein B receptor Proteins

Many biological assays use antibodies to detect Apolipoprotein B receptor, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Apolipoprotein B receptor in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Apolipoprotein B receptor antibodies...

We validate the specificity of these antibodies to Apolipoprotein B receptor by testing them on tissues known to express APOBR positively and negatively. Browse below to find the APOBR antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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APOBR Infographic by Boster Bio

All APOBR Products

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Anti-Apolipoprotein B receptor APOBR Antibody

Western blot (WB) analysis of APOBR polyclonal antibody at 1:500 dilution
Lane1:A549 whole cell lysate
Lane2:MCF-7 whole cell lysate
Lane3:PC12 whole cell lysate

Immunohistochemistry (IHC) analyzes of APOBR pAb in paraffin-embedded human rectum carcinoma tissue at 1:50,showing cytoplasmic staining

Human, Rat

IHC, WB

$405
Cat # A09242
100ul

Anti-APOB48R (APOBR) Mouse Monoclonal Antibody [Clone ID: OTI1B1]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY APOBR (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (10ug) from 1 cell line by using anti-APOBR monoclonal antibody at 1:200 dilution

Human

IHC, WB

$523
Cat # M09242
100 µl

APOB48R (APOBR) (NM_018690) Human Over-expression Lysate

Human

$960
Cat # LS055911
20 µg, 100 µg

APOBR Overview

Facts about Apolipoprotein B receptor.

APOBR 3D structure. Source: alphafold

Apolipoprotein B receptor (APOBR)

Macrophage receptor which binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a similar domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). Binds and internalizes TRL when from the context of the macrophage.

May provide essential lipids to reticuloendothelial cells. Could also be involved in foam cell formation with elevated TRL and remnant lipoprotein (RLP).

Gene Information

Human
Gene Name:	APOBR
Uniprot:	Q0VD83
Entrez:	55911

Family

Belongs to:

No superfamily

Alternative Names

APOB100R; apoB-48R; APOB48Rapolipoprotein B48 receptor; apolipoprotein B receptor; Apolipoprotein B-100 receptor; Apolipoprotein B-48 receptor

Molecular Weight

Mass (kDA):
115.634 kDA

Genomic Context


Human

Location:	16p12.1
Sequence:	16; NC_000016.10 (28494643..28498964)

Tissue Specificity

Expressed in peripheral blood leukocytes > bone marrow = spleen > lymph node, and only faintly visible in appendix and thymus. Expressed in the brain, heart, kidney, liver, lung, pancreas, and placenta. Expressed primarily by reticuloendothelial cells: monocytes, macrophages, and endothelial cells. Expressed in atherosclerotic lesion foam cells.

Subcellular Localizations

Cell membrane; Peripheral membrane protein. Binds monocyte-macrophage membrane. Thought to be anchored in the membrane through an interaction with an integral membrane protein.

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/APOBR

References

PMID: 10852956 by Brown M.L., et al. A macrophage receptor for apolipoprotein B48: cloning, expression, and atherosclerosis.

PMID: 10191299 by Bradley W.A., et al. Antipeptide antibodies reveal interrelationships of MBP 200 and MBP 235: unique apoB-specific receptors for triglyceride-rich lipoproteins on human monocyte-macrophages.