Artemin Antibodies

AND ARTN ELISA kits, Artemin Proteins

Many biological assays use antibodies to detect Artemin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Artemin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Artemin antibodies...

We validate the specificity of these antibodies to Artemin by testing them on tissues known to express ARTN positively and negatively. Browse below to find the ARTN antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ARTN Infographic by Boster Bio

All ARTN Products

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Product

Figures

Specificity

Applications

Price

Human Artemin ELISA Kit PicoKine®

7 Q&As

Human

ELISA

$499
Cat # EK1534
96 wells/kit, with removable strips.

Mouse Artemin ELISA Kit PicoKine®

7 Q&As

Mouse

ELISA

$499
Cat # EK1535
96 wells/kit, with removable strips.

Anti-Artemin Artn Antibody

Human, Mouse, Rat

ELISA, IF, IHC

$380
Cat # A05102-1
100ul

Artemin (ARTN) (NM_057091) Human Over-expression Lysate

Artemin (ARTN) Human Over-expression Lysates NM_001136215

Human

$628
Cat # LS009048
20 µg, 100 µg

ARTN Overview

Facts about Artemin.

ARTN 3D structure. Source: alphafold

Artemin (ARTN)

Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and supports the survival of dopaminergic neurons of the ventral mid-brain.

Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a significant part of the gut-associated lymphoid tissue. .

Gene Information

Human
Gene Name:	ARTN
Uniprot:	Q5T4W7
Entrez:	9048

Family

Belongs to:

TGF-beta family

Alternative Names

Artemin; ARTN; Enovin; EVN; EVNneurotrophic factor; NBN; Neublastin

Molecular Weight

Mass (kDA):
22.878 kDA

Genomic Context


Human

Location:	1p34.1
Sequence:	1; NC_000001.11 (43933320..43937240)

Tissue Specificity

Ubiquitous. Expressed at high levels in peripheral tissues including prostate, placenta, pancreas, heart, kidney, pituitary gland, lung and testis. Expressed at low levels in the brain.

Subcellular Localizations

Secreted.

Diseases

Pain
Nervousness
Carcinoma
Neoplasms
Cell Invasion
Neuralgia
Nerve Damage
Neoplasm Invasiveness
Neoplasm Metastasis
Peripheral Nerve Injuries
Hyperalgesia
Crest Syndrome

Malignant Neoplasm Of Breast
Malignant Neoplasms
Peripheral Neuropathy
Hypertrophy
Parkinson Disease
Malignant Neoplasm Of Pancreas
Tissue Adhesions

Interacting Proteins

GFRA3

Pathways

Regeneration
Innervation
Cell Death
Cell Proliferation
Cell Adhesion
Cell Migration
Hypersensitivity
Neuron Development
Localization
Kidney Morphogenesis
System Development
Nervous System Development
Pathogenesis

Transport
Neural Crest Cell Migration
Gene Silencing
Brain Development
Aging
Tube Formation
Axon Regeneration

PTMs

Phosphorylation

Cleavage

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ARTN

References

PMID: 9883723 by Baloh R.H., et al. Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex.

PMID: 10583383 by Masure S., et al. Enovin, a member of the glial cell-line-derived neurotrophic factor (GDNF) family with growth promoting activity on neuronal cells. Existence and tissue-specific expression of different splice variants.