ATAD2 Antibodies

AND ATAD2 ELISA kits, ATAD2 Proteins

Many biological assays use antibodies to detect ATAD2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ATAD2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ATAD2 antibodies...

We validate the specificity of these antibodies to ATAD2 by testing them on tissues known to express ATAD2 positively and negatively. Browse below to find the ATAD2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ATAD2 Infographic by Boster Bio

All ATAD2 Products

Product

Figures

Specificity

Applications

Price

Anti-ATAD2 Antibody (N-term)

Human

$298
Cat # A03855
80 µl

Anti-ATAD2 Rabbit Monoclonal Antibody

Human

Flow Cytometry, IF, ICC, WB

$370
Cat # M03855
100 μl/vial

ATAD2 Overview

Facts about ATPase family AAA domain-containing protein 2.

ATAD2 3D structure. Source: alphafold

ATPase family AAA domain-containing protein 2 (ATAD2)

May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters.

Might be required for histone hyperacetylation. Involved from the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.

Gene Information

Human
Gene Name:	ATAD2
Uniprot:	Q6PL18
Entrez:	29028

Family

Belongs to:

AAA ATPase family

Alternative Names

AAA nuclear coregulator cancer-associated protein; ANCCA; ANCCAMGC131938; ATAD2; ATPase family AAA domain-containing protein 2; ATPase family, AAA domain containing 2; CT137; DKFZp667N1320; EC 3.6.1.3; MGC142216; MGC29843; MGC5254; PRO2000

Molecular Weight

Mass (kDA):
158.554 kDA

Genomic Context


Human

Location:	8q24.13
Sequence:	8; NC_000008.11 (123319850..123396447, complement)

Tissue Specificity

Highly expressed in estrogen receptor positive breast tumors and in osteosarcoma tumors.

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Breast
Cell Transformation, Neoplastic
Aortic Aneurysm, Abdominal
Neoplasm Metastasis
Carcinoma
Mammary Neoplasms
Malignant Neoplasm Of Prostate
Malignant Neoplasm Of Lung
Malignant Paraganglionic Neoplasm

Prostatic Neoplasms
Fracture Of First Cervical Vertebra
Tumor Progression
Colonic Neoplasms
Malignant Tumor Of Colon
Bone Neoplasms

Interacting Proteins

ESR1
NCOA3

Pathways

Cell Proliferation
Cell Cycle
Transport
Methylation
S Phase
Pathogenesis
Mitosis
Dna Methylation
Response To Drug
Localization

Cytoskeleton Organization
Response To 5-fluorouracil
Chromatin Assembly
Oncogenesis

PTMs

Acetylation

Methylation

Research Areas

Protein Phosphatase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ATAD2

References

PMID: 15334068 by Petroziello J., et al. Suppression subtractive hybridization and expression profiling identifies a unique set of genes overexpressed in non-small-cell lung cancer.

PMID: 11483580 by Yu Y., et al. Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs.