Atat1 Antibodies

AND Atat1 ELISA kits, Atat1 Proteins

Many biological assays use antibodies to detect Atat1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Atat1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Atat1 antibodies...

We validate the specificity of these antibodies to Atat1 by testing them on tissues known to express Atat1 positively and negatively. Browse below to find the Atat1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Atat1 Infographic by Boster Bio

All Atat1 Products

Product

Figures

Specificity

Applications

Price

C6orf134 (ATAT1) (NM_001031722) Human Over-expression Lysate

Human

$628
Cat # LS079969
100 µg

Atat1 Overview

Facts about Alpha-tubulin N-acetyltransferase 1.

Alpha-tubulin N-acetyltransferase 1 (Atat1)

Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin using a slow enzymatic rate, because of catalytic site that is not optimized for acetyl transfer.

Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules due to its slow acetylation rate as it does not have sufficient time to act on dynamically unstable microtubules before the enzyme is released.

Gene Information

Mouse
Gene Name:	Atat1
Uniprot:	Q8K341
Entrez:	73242

Family

Belongs to:

acetyltransferase ATAT1 family

Alternative Names

Acetyltransferase MEC-17; alpha tubulin acetyltransferase 1; alpha-TAT; alpha-tubulin N-acetyltransferase; C6orf134; chromosome 6 open reading frame 134; DKFZp547J097; EC 2.3.1.108; Em:AB023049.7; FLJ13158; MEC17Nbla00487; TAT

Molecular Weight

Mass (kDA):
47.164 kDA

Genomic Context


Mouse

Location:	17\|17 B1
Sequence:	17;

Tissue Specificity

Widely expressed with highest levels in neuronal tissues. In the brain, expressed in the cortex, cerebellum and hippocampus, including the pyramidal layers in CA1 and CA3, as well as the granular cell layers in the lateral blade (suprapyramidal portion) and the medial blade (infrapyramidal portion) of the dentate gyrus. In testis, mainly expressed in the internal cell layers of seminiferous tubules, where spermatocytes and spermatids are located.

PTMs

Acetylation

Methylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Atat1

References

PMID: 20829795 by Akella J.S., et al. MEC-17 is an alpha-tubulin acetyltransferase.

PMID: 23720746 by Kim G.W., et al. Mice lacking alpha-tubulin acetyltransferase 1 are viable but display alpha-tubulin acetylation deficiency and dentate gyrus distortion.