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- Table of Contents
Designing an IHC experiment for ATP6V1C1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the ATP6V1C1 IHC GuideFacts about V-type proton ATPase subunit C 1.
Subunit of the peripheral V1 complex of vacuolar ATPase.
Subunit C is essential for the assembly of the catalytic sector of the enzyme and is very likely to have a specific role in its catalytic activity.V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. .
| Human | |
|---|---|
| Gene Name: | ATP6V1C1 |
| Uniprot: | P21283 |
| Entrez: | 528 |

| Belongs to: |
|---|
| V-ATPase C subunit family |

ATP6CH+-transporting ATPase chain C, vacuolar; ATP6Dsubunit C of vacuolar proton-ATPase V1 domain; ATPase, H+ transporting, lysosomal (vacuolar proton pump) 42kD; ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C, isoform 1; ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1; FLJ20057; H(+)-transporting two-sector ATPase, subunit C; vacuolar ATP synthase subunit C; vacuolar proton pump C subunit; Vacuolar proton pump subunit C 1; vacuolar proton pump, 42-kD subunit; vacuolar proton-ATPase, subunit C, VI domain; VATCH+ -ATPase C subunit; V-ATPase C subunit; V-ATPase subunit C 1; Vma5;
Mass (kDA):
43.942 kDA

| Human | |
|---|---|
| Location: | 8q22.3 |
| Sequence: | 8; NC_000008.11 (103021083..103073051) |
Ubiquitous.




PMID: 8250920 by van Hille B., et al. Cloning and tissue distribution of subunits C, D, and E of the human vacuolar H(+)-ATPase.
PMID: 11707601 by Tanner S.M., et al. BAALC, the human member of a novel mammalian neuroectoderm gene lineage, is implicated in hematopoiesis and acute leukemia.