Best Uses Of The CDC27 Marker From Boster Bio

There are many reasons to use an antibody against CDC27. The antibody is highly specific and high affinity, thereby making it a valuable tool for your research. Boster Bio has a dedicated team that validates its products on multiple platforms. For this reason, Boster rewards those who review the products the first time with product credits. Boster also offers rewards programs to support scientists from all over the globe.

Anti-CDC27 Marker

Boster Bio sells Anti-CDC27 Marker which is a specific antibody that detects CDC27 protein in cells. This antibody reacts to cells from Rat, Mouse, and Human. Boster Bio supplies highly purified antibodies for research. Their antibodies are also highly specific and affinity-validated. Boster Bio offers product credits to all scientists, as a reward, for first-time product reviews.

This antibody targets Cdc27 subunits of APC (anaphase-promoting complex). This regulates the rate of mitosis. It is highly phosphorylated, and is associated to the kinetochores. However, dephosphorylated Cdc27 was associated with isolated chromosomes, suggesting that CDC27 is an important protein involved in mitosis.

The results of this study showed that mir-218-2 inhibits in vivo growth of glioma-cells. The researchers implanted U87-cells into male BALB/c Nude mice. The animals were then weighed 30 days later. The tumors in mice with CDC27 inhibited cells were smaller than those of mice with CGs. They also had lower levels Ki67 and CDC27. This indicates that the overexpression of mir-218-2 inhibits glioma cell growth.

Anti-Cdh2

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References

PMID: 8234252 by Tugendreich S., et al. Linking yeast genetics to mammalian genomes: identification and mapping of the human homolog of CDC27 via the expressed sequence tag (EST) data base.

PMID: 7756179 by Chen P.L., et al. Identification of a human homologue of yeast nuc2 which interacts with the retinoblastoma protein in a specific manner.