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- Table of Contents
CDC27 Antibodies
AND CDC27 ELISA kits, CDC27 Proteins
Many biological assays use antibodies to detect CDC27, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CDC27 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CDC27 antibodies...
Designing a Western blot for CDC27? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CDC27 Western Blot GuideDesigning an IHC experiment for CDC27? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the CDC27 IHC GuideCDC27 Infographic by Boster Bio
All CDC27 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03905-3
100 μg/vial
Cat # A03905-3
100 μg/vial
Human, Mouse
ELISA
$540
Cat # EKC2285
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2285
1 kit, containing two 96-well plates and all necessary reagents
CDC27 Overview
Facts about Cell division cycle protein 27 homolog.
Cell division cycle protein 27 homolog (CDC27)
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of'Lys-48'- and'Lys-63'-linked polyubiquitin chains.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | CDC27 |
| Uniprot: | P30260 |
| Entrez: | 996 |
Family
| Belongs to: |
|---|
| APC3/CDC27 family |
Alternative Names
ANAPC3CDC27 homolog; anaphase promoting complex subunit 3; Anaphase-promoting complex subunit 3; anaphase-promoting complex, protein 3; APC 3; APC3cell division cycle 27; CDC27Hs; cell division cycle 27 homolog (S. cerevisiae); cell division cycle protein 27 homolog; D0S1430E; D17S978E; HNUC; H-NUC; nuc2 homolog; NUC2
Molecular Weight
Mass (kDA):
91.867 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q21.32 |
| Sequence: | 17; NC_000017.11 (47117703..47189295, complement) |
Subcellular Localizations
Nucleus.
Diseases
- Malignant Neoplasms
- Neoplasms
- Aneuploidy
- Mammary Neoplasms
- Malignant Neoplasm Of Breast
- Nervousness
- Melanoma
- Carcinoma
- Cleft Palate
- Cleft Lip
- Cell Invasion
- Lung Neoplasms
Interacting Proteins
- ANAPC4
- CCND1
- CDC20
- CDH1
- FBXO5
- FOXO3
- FZR1
- MAD2L1
- MAD2L2
- NCK1
Pathways
- Mitosis
- Cell Cycle
- Anaphase
- Metaphase
- Proteolysis
- Dna Replication
- Cell Division
- S Phase
- Exit From Mitosis
- Interphase
- Spindle Checkpoint
- Chromosome Segregation
- Localization
PTMs
- Phosphorylation
- Ubiquitination
- Dephosphorylation
Research Areas
- Cell Cycle and Replication
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDC27
bosterbio.com/bosterbio-gene-info-cards/CDC27
References
PMID: 8234252 by Tugendreich S., et al. Linking yeast genetics to mammalian genomes: identification and mapping of the human homolog of CDC27 via the expressed sequence tag (EST) data base.
PMID: 7756179 by Chen P.L., et al. Identification of a human homologue of yeast nuc2 which interacts with the retinoblastoma protein in a specific manner.