CDK12 Antibodies

AND CDK12 ELISA kits, CDK12 Proteins

Many biological assays use antibodies to detect CDK12, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CDK12 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CDK12 antibodies...

We validate the specificity of these antibodies to CDK12 by testing them on tissues known to express CDK12 positively and negatively. Browse below to find the CDK12 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CDK12 Infographic by Boster Bio

All CDK12 Products

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Product

Figures

Specificity

Applications

Price

Anti-Cyclin-dependent kinase 12 CDK12 Antibody

Human, Rat

ELISA, WB

$380
Cat # A03495
100ul

Anti-CDK12 Antibody Picoband®

Human

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A03495-1
100 μg/vial

CrkRS (CDK12) (NM_016507) Human Over-expression Lysate

Human

$960
Cat # LS051755
100 µg

CDK12 Overview

Facts about Cyclin-dependent kinase 12.

CDK12 3D structure. Source: alphafold

Cyclin-dependent kinase 12 (CDK12)

Cyclin-dependent kinase which phosphorylates the C- terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key regulator of transcription elongation. Regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability.

Preferentially phosphorylates'Ser-5' in CTD repeats which are currently phosphorylated at'Ser-7', but could also phosphorylate'Ser-2'. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2.

Gene Information

Human
Gene Name:	CDK12
Uniprot:	Q9NYV4
Entrez:	51755

Family

Belongs to:

protein kinase superfamily

Alternative Names

Cdc2-related kinase, arginine/serine-richCrkRS; Cell division cycle 2-related protein kinase 7; Cell division protein kinase 12; CRK7CDC2-related protein kinase 7; CRKR; CRKRS; cyclin-dependent kinase 12; EC 2.7.11; EC 2.7.11.23; hCDK12; KIAA0904EC 2.7.11.22