Cop1 Antibodies

AND Cop1 ELISA kits, Cop1 Proteins

Many biological assays use antibodies to detect Cop1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cop1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cop1 antibodies...

We validate the specificity of these antibodies to Cop1 by testing them on tissues known to express Cop1 positively and negatively. Browse below to find the Cop1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Cop1 Infographic by Boster Bio

All Cop1 Products

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Product

Figures

Specificity

Applications

Price

Anti-RFWD2 COP1 Antibody

Western blot analysis of extracts of various cell lines, using RFWD2 antibody at 1:1000 dilution

Human, Mouse, Rat

IHC, WB

$405
Cat # A31677
100ul

COP1 (RFWD2) (NM_001001740) Human Recombinant Protein

Coomassie blue staining of purified COP1 protein

$1062
Cat # PROTQ8NHY2
20 µg

COP1 (RFWD2) (NM_022457) Human Over-expression Lysate

COP1 (RFWD2) Human Over-expression Lysates NM_001001740

Human

$628
Cat # LS064326
20 µg, 100 µg

Cop1 Overview

Facts about E3 ubiquitin-protein ligase COP1.

E3 ubiquitin-protein ligase COP1 (Cop1)

E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Involved in JUN ubiquitination and degradation.

Directly involved in p53 (TP53) ubiquitination and degradation, thereby abolishing p53-dependent transcription and apoptosis. Ubiquitinates p53 independently of MDM2 or RCHY1.

Gene Information

Mouse
Gene Name:	Cop1
Uniprot:	Q9R1A8
Entrez:	26374

Family

Belongs to:

COP1 family

Alternative Names

E3 ubiquitin-protein ligase COP1

Molecular Weight

Mass (kDA):
80.441 kDA

Genomic Context


Mouse

Location:	1\|1 H1
Sequence:	1;

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Cop1

References

PMID: 10395541 by Wang H., et al. Evidence for functional conservation of a mammalian homologue of the light-responsive plant protein COP1.