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- Table of Contents
Cystatin-SN Antibodies
AND CST1 ELISA kits, Cystatin-SN Proteins
Many biological assays use antibodies to detect Cystatin-SN, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cystatin-SN in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cystatin-SN antibodies...
Designing an IHC experiment for Cystatin-SN? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the CST1 IHC GuideCST1 Infographic by Boster Bio
All CST1 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$500
Cat # EZ1654
5 plates/kit
Cat # EZ1654
5 plates/kit
Human
ELISA
$499
Cat # EK1654
96 wells/kit, with removable strips.
Cat # EK1654
96 wells/kit, with removable strips.
CST1 Overview
Facts about Cystatin-SN.
Cystatin-SN (CST1)
Human saliva seems to include several cysteine proteinase inhibitors which are immunologically related to cystatin S but that differ in their specificity because of amino acid sequence differences. Cystatin SN, with a pI of 7.
5, is a much better inhibitor of papain and dipeptidyl peptidase I than is cystatin S, although both inhibit ficin equally well. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CST1 |
| Uniprot: | P01037 |
| Entrez: | 1469 |
Family
| Belongs to: |
|---|
| cystatin family |
Alternative Names
CST1; cystain-SA-I; cystatin 1; cystatin SA-I; Cystatin SN; cystatin-1; cystatin-SN; Salivary cystatin-SA-1; type 2 family
Molecular Weight
Mass (kDA):
16.388 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 20p11.21 |
| Sequence: | 20; NC_000020.11 (23747553..23750937, complement) |
Tissue Specificity
Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in saliva, tears, urine and seminal fluid.
Subcellular Localizations
Secreted.
Diseases
- Malignant Neoplasms
- Neoplasms
- Cell Transformation, Neoplastic
- Neoplasm Metastasis
- Malignant Tumor Of Colon
- Colorectal Cancer
- Colorectal Neoplasms
- Adrenal Hyperplasia
- Acquired Immunodeficiency Syndrome
- Stomach Neoplasms
- Periodontitis
Interacting Proteins
- SGTA
Pathways
- Pathogenesis
- Senescence
- Cell Adhesion
- Flight
- Cell Proliferation
- Cell Motility
- Cell Death
- Cellular Senescence
- Immune Response
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CST1
bosterbio.com/bosterbio-gene-info-cards/CST1
References
PMID: 3446578 by Saitoh E., et al. Human cysteine-proteinase inhibitors: nucleotide sequence analysis of three members of the cystatin gene family.
PMID: 2837486 by Al-Hashimi I., et al. Purification, molecular cloning, and sequencing of salivary cystatin SA-1.