CYP24A1 Antibodies

1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (CYP24A1)

Has a role in maintaining calcium homeostasis. Catalyzes the adrenodoxin-dependent 24-hydroxylation of calcidiol (25- hydroxyvitamin D(3)) and calcitriol (1-alpha,25-dihydroxyvitamin D(3)).

The receptor can do up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also reveals 23- hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product.

Gene Information

Human
Gene Name:	CYP24A1
Uniprot:	Q07973
Entrez:	1591

Family

Belongs to:
cytochrome P450 family

Alternative Names

25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; CP241; CYP241,25-alphadihydroxyvitamin D3 24-hydroxylase; Cytochrome P450 24A1; cytochrome P450, family 24, subfamily A, polypeptide 1,24-OHase; cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase); Cytochrome P450-CC24; EC 1.14.13.n4; exo-mitochondrial protein; MGC126273; MGC126274; P450-CC24; vitamin D 24-hydroxylase; Vitamin D(3) 24-hydroxylase

Molecular Weight

Mass (kDA):
58.875 kDA

Genomic Context

Human
Location:	20q13.2
Sequence:	20; NC_000020.11 (54145731..54174032, complement)

Subcellular Localizations

Mitochondrion.

Diseases

• Malignant Neoplasms
• Neoplasms
• Vitamin D Deficiency
• Prostatic Neoplasms
• Malignant Neoplasm Of Prostate
• Malignant Neoplasm Of Breast
• Kidney Diseases
• Chronic Kidney Disease
• Hypercalcemia
• Rickets
• Mammary Neoplasms
• Malignant Paraganglionic Neoplasm
• Carcinoma

• Sclerosis
• Diabetes Mellitus
• Colonic Neoplasms
• Malignant Tumor Of Colon
• Colorectal Neoplasms
• Multiple Sclerosis
• Asthma

Pathways

• Cell Proliferation
• Transport
• Cell Growth
• Pathogenesis
• Cell Differentiation
• Methylation
• Aging
• Cell Cycle
• Dna Methylation
• Response To Vitamin
• Response To Vitamin D
• Sensitization
• Cell Activation

• Immune Response
• Translation
• Hair Cycle
• Excretion
• Electron Transport
• Osteoblast Differentiation
• Ossification

PTMs

• Hydroxylation
• Oxidation
• Methylation

• Acetylation
• Cleavage
• Phosphorylation

• Sumoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CYP24A1

Best Uses Of The CYP24A1 Marker

As a new researcher you're likely to ask what the best methods to optimize Boster Bio are. Boster Bio users are encouraged to read their guides to optimize their experiments. Troubleshooting guides and optimization tips can help you eliminate a variety of sources of error and enhance your results. There is no doubt that any researcher will face problems during their experiments. A Boster Bio troubleshooting guide will aid you in understanding how to fix the most frequently encountered issues and get your research back on the right track.

Boster Bio optimization tips

Every experiment will come with challenges. Boster Bio can help you by providing tips for optimization and guidelines. To ensure that your results are reliable, ensure you follow the protocols when making your sample. The flow procedures can be quite complicated so it is recommended to read the instructions before beginning your experiment. Make sure to include appropriate controls as well as an instruction manual for preparing your sample.

Boster Bio troubleshooting guides

The Troubleshooting Guide for Immunohistochemistry from Boster Bio provides a comprehensive overview of the most important IHC methods and protocols. It's designed to help researchers overcome a range of challenges, ranging from background issues to nonspecific staining so that they can obtain the most precise results. The guide also offers valuable optimization strategies. To ensure the success of your next project, you can refer to the troubleshooting guide prior to executing the experiment.

Boster Bio history

Steven Boster, a late 90s entrepreneur, invented his first product in the late 90s. He earned the nickname "he that converts science into a lavatory." Since since then, Boster has created various products for IHC and ELISA. Boster was China's biggest antibody catalog by the close of the 1990s. PicoKine(tm) is an exclusive ELISA platform, was developed by Boster. It makes a high-sensitivity ELISA kit.