Dedicator of cytokinesis protein 2 (DOCK2)

Involved in cytoskeletal rearrangements necessary for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which deals bound GDP for free GTP.

May also take part in IL2 transcriptional activation via the activation of RAC2. .