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We validate the specificity of these antibodies to GGT1 by testing them on tissues known to express GGT1 positively and negatively. Browse below to find the GGT1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.
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Facts about Glutathione hydrolase 1 proenzyme.
In the presence of high concentrations of dipeptides and a few amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine source and contributes to maintain intracellular GSH level.
CD224 antigen; CD224; D22S672; D22S732; EC 220.127.116.11; gamma-glutamyl transpeptidase; gamma-glutamyltransferase 1MGC96904; gamma-glutamyltranspeptidase 1; GGT 1; GGTMGC96963; glutamyl transpeptidase; GTG; MGC96892
|Sequence:||22; NC_000022.11 (24583750..24629005)|
Detected in fetal and adult kidney and liver, adult pancreas, stomach, intestine, placenta and lung. Isoform 3 is lung-specific. There are several other tissue-specific forms that arise from alternative promoter usage but that produce the same protein.
Cell membrane; Single-pass type II membrane protein.