GGT1 Antibodies

AND GGT1 ELISA kits, GGT1 Proteins

Many biological assays use antibodies to detect GGT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GGT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GGT1 antibodies...

We validate the specificity of these antibodies to GGT1 by testing them on tissues known to express GGT1 positively and negatively. Browse below to find the GGT1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CCN2 Next: GGT3P

GGT1 Infographic by Boster Bio

All GGT1 Products

Product

Figures

Specificity

Applications

Price

Anti-GGT1 Antibody

Human, Mouse, Rat

$405
Cat # A02340
100ul

Anti-GGT1 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A02340-1
100ul

Anti-GGT1 Rabbit Monoclonal Antibody

Human

IHC, WB

$370
Cat # M02340
100 μl/vial

GGT1 (NM_005265) Human Over-expression Lysate

Human

$628
Cat # LS002678
100 µg

GGT1 Overview

Facts about Glutathione hydrolase 1 proenzyme.

GGT1 3D structure. Source: alphafold

Glutathione hydrolase 1 proenzyme (GGT1)

Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases.

In the presence of high concentrations of dipeptides and a few amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine source and contributes to maintain intracellular GSH level.

Gene Information

Human
Gene Name:	GGT1
Uniprot:	P19440
Entrez:	2678

Family

Belongs to:

gamma-glutamyltransferase family

Alternative Names

CD224 antigen; CD224; D22S672; D22S732; EC 2.3.2.2; gamma-glutamyl transpeptidase; gamma-glutamyltransferase 1MGC96904; gamma-glutamyltranspeptidase 1; GGT 1; GGTMGC96963; glutamyl transpeptidase; GTG; MGC96892

Molecular Weight

Mass (kDA):
61.41 kDA

Genomic Context


Human

Location:	22q11.23
Sequence:	22; NC_000022.11 (24583750..24629005)

Tissue Specificity

Detected in fetal and adult kidney and liver, adult pancreas, stomach, intestine, placenta and lung. Isoform 3 is lung-specific. There are several other tissue-specific forms that arise from alternative promoter usage but that produce the same protein.